Antiphospholipids Antibodies and Migraine

Background: Antiphospholipids antibodies has been associated with non-thrombotic neurological conditions such as migraine. We set out to estimate the concentration of antiphospholipids antibody among patients with migraine and normal population. Methods: This is prospective case-control study of 158 subjects including 82 migraine patients who fulfilled the International Headache Society criteria for the diagnosis of migraine headache and 76 age and sex-matched controls who were mostly hospital staff and medical students. Blood samples were taken for quantification of antiphospholipids antibodies. Results: There were 28 males and 54 females among the migraine patients and 30 males and 46 females among the controls. Their mean ages were 28.8 + 8.4 years and 26.4 + 3.9 years; respectively. Migraine patients had increased level of aPL (lgG anti Beta2GP1) 27.76 + 14.47IU/ml compared to the normal healthy adults (21.43 + 9.4IU/ml) (p0.05). Similarly; antiphospholipid antibodies was significantly elevated in migraine patients with aura compared to those without aura; (?2

Subarachnoid haemorrhage - changing trends

Bleeding into the subarachnoid space (Subarachnoid Haemorrhage - SAH) is a dramatic and potentially fatal event that should not be missed. Modern trends have seen a decline in morbidity and mortality mainly due to advancements in neuroradiology and neurosurgical techniques coupled with early intervention. The review presents the problems faced in the past and highlights the developments in various aspects of this catastrophic disease whose morbidity and mortality remain unacceptably high despite the improvements