RMJ research series: literature searching

MY EXPERIENCE:Christian is a year 5 medical student in Rwanda embarking on his first research project.I had never undertaken a formal literature search until my 5th year of medical studies, I was therefore very much challenged by how rigorous it was. For the fist time, I had to use websites like PubMed, Cochrane to find the information I needed. This replaced my usual sources of information which had been Wikipedia and Google. I then had to learn how to use a reference manager, Mendeley, to store and cite the papers I found. I was using it and so many terms I hadn't heard of before. It was all unfamiliar to me.I found it really difficult to find relevant papers in PubMed and because of the scarcity of papers and poor internet connection I found it really discouraging.Organizing articles and summarizing them was the hardest of all. Multiple pages of conference reports, articles and surveys all were to be transformed into relevant systematically coordinated summary.As a solution to these problems I used the Mendeley literature search which contains an abundance of articles. I then hand-searched the bibliographies of the articles I had found. To overcome problems of internet connection I would work in places with strong Wi-Fi and spend the whole day nonstop searching and downloading everything ready for offline reading and reviewing.So, as a result, my research project got quicker, more organized, more comprehensible and I found this really satisfying

Assessment of Scholarly Publications of Nigerian Health Sciences Researchers in MEDLINE/Pubmed (1996-2007)

Scholarly publications are outcome of research and are important channels for dissemination of research findings by researchers. The main objective of this study was to assess the scholarly publications of Nigerian health sciences' researchers and the journals in which they publish. Health science researchers are health care providers; faculty; medical scientists and other allied health professionals who conduct research in health related fields. Research articles written by Nigerian health sciences' researchers published during 1996-2007 were accessed through the MEDLINE/PubMed database. Both the author affiliation in Address field and Publication date field were used to obtain data on the number and characteristics of publications by the researchers. A total of 7030 articles were published during the period. The number of publications increased from 338 in 1996 to 952 in 2007. Of the 7;030 citations; 2;124 (31) were published in nine Nigerian journals with the African Journal of Medicine and Medical Sciences having the highest (660). However; 17 articles were published in four international multidisciplinary journals namely: British Medical Journal (BMJ); Journal of the American Medical Association (JAMA); Lancet and New England Journal of Medicine (NEJM). Approximately 80 of the publications were Original Research Articles. Nigerian health sciences' researchers are productive in terms of scholarly publications. However; their publications are concentrated more in national journals; some of which are not indexed in any bibliographic database; others are print only; not widely circulated thereby limiting the impact of their research. Development of a national bibliographc database to index articles published in Nigerian journals and publication of more journal in electronic format is recommended

Using Lot Quality Assurance Sampling Methodology to Evaluate the Uthukela District Child Survival Project of Kwazulu-Natal

Abstract:Health services programmes and interventions require objective measures on coverage and quality to ensure that managers have the evidence to adopt and expand health interventions effectively and efficiently. Over the past 15 years; the uThukela District Child Survival Project of South Africa achieved this through regular two- to three-year project evaluations using cluster sampling. Results of these surveys have improved the ability of Child Survival Projects to identify priorities; define objectives based on data; and measure progress towards these objectives. However; the inability to disaggregate information to composite Supervision Areas (SAs) was a limitation. Lot quality assurance sampling (LQAS) was adopted as an improved method based on its ability to assess performance in disaggregated units within a study population and to reliably compare coverage and health status indicators for routine monitoring of child survival activities. This study assessed the feasibility and reliability of LQAS to evaluate the Child Survival Project and compare the results of a rapid manual analysis with a secondary electronic analysis of the same data. The accuracy of the manual analysis was comparable and provides evidence that LQAS and rapid manual analysis can be used to evaluate intervention programmes; particularly in settings of limited electronic technology and expertise

A database of antimalarial drug resistance

A large investment is required to develop; license and deploy a new antimalarial drug. Too often; that investment has been rapidly devalued by the selection of parasite populations resistant to the drug action. To understand the mechanisms of selection; we need detailed information on the patterns of drug use in a variety of environments; and the geographic and temporal patterns of resistance that result. Currently; there is no publically accessible central database that contains information on the levels of resistance to antimalaria drugs. This paper outlines the resources that are available; and the steps that might be taken to create a dynamic; open access database that would include current and historical data on clinical efficacy; in vitro responses and molecular markers related to drug resistance in P. falciparum and P. vivax. The goal is to include historical and current data on resistance to commonly used drugs like chloroquine and sulfadoxine-pyrimethamine; and on the many combinations that are now being tested in different settings. The database will be accessible to all on the Web. The information in such a database will inform optimal utilization of current drugs and sustain the longest possible therapeutic life of newly introduced drugs and combinations. The database will protect the valuable investment represented by the development and deployment of novel therapies for malaria