Epidemiological and clinicopathological profile of endometrial cancer in Gabon

Introduction: L'objectif général de notre travail était d'apporter une description épidémiologique et clinicopathologique du cancer de l'endomètre au Gabon. Patients et méthode: Cette étude descriptive et rétrospective a été réalisée à l'Institut de Cancérologie de Libreville chez les patientes atteintes du cancer de l'endomètre sur une période de 7 années (de janvier 2012 à octobre 2018). Résultats: Cette étude a inclus 32 patientes et les résultats obtenus ontmontré que ce cancer au Gabon est plus fréquent chez la femme multipare, que histologiquement le type 1 est le plus souvent rencontré et que ce cancer est de haut grade de malignité. De ce travail ressort également la difficulté du suivi des patientes. Conclusion: Le cancer de l'endomètre étant un cancer souvent d'emblée de mauvais pronostic, il est d'intérêt de mettre en place une stratégie de prévention et de management adapté.Mots clés: cancer, endomètre, étude clinicopathologique, suivi, Gabon Abstract:Introduction:The general objective of our work was to provide an epidemiological and clinicopathological description of endometrial cancer in Gabon.

Introduction: The general objective of our work was to provide an epidemiological and clinicopathological description of endometrial cancer in Gabon. Epidemiological and clinicopathological profile of... Patients and method: This descriptive and retrospective study was carried out at Cancer Institute of Libreville in patients with endometrial cancer over a period of 7 years (from January 2012 to October 2018) . Results: This study included 32 patients and the results obtained showed that this cancer in Gabon is more frequent in multiparous women, that histologically type 1 is most often encountered and that this cancer is of high grade malignancy. This work also shows the difficulty of following up patients. Conclusion: As endometrial cancer is often a cancer with a poor prognosis , it is interest to put in place an appropriate prevention and management strategy.

Assessment of the prevalence of abnormal hysteroscopic findings in infertile women undergoing ART

Background: The endometrium plays an important role in implantation of good quality embryos in ART. Many studies have proved the negative impact of intra uterine pathologies on reproductive outcome whether spontaneous pregnancy or ART, because uterine anomalies may be associated with many obstetric complications such as miscarriage, preterm birth, premature rupture of membrane, malpresentation, postpartum bleeding and retained placenta. Aim of the work: This study aims to assess the prevalence of abnormal hysteroscopic findings among infertile women undergoing ART at Ain Shams Maternity University Hospital over the period from January 2007 to January 2017. Patients and Methods: This descriptive retrospective study was carried out on infertile couples planned for ART who were sent to ECDU for hysteroscopy in Early Cancer Detection Unit (ECDU), Ain Shams University Maternity Hospital. Case reports From January 2007 to January 2017 were reviewed. Results: The most prevalent congenital abnormality was endometrial polyp (18.4%) followed by uterine septum (6.9%). Conclusion: This study concluded that the most common uterine abnormality was endometrial polyp (18.4%), followed by uterine septum in 6.9% of patients. Also, thick endometrium was very common with a prevalence of 12.9%. Therefore, based on this high prevalence of abnormalities, this study is in agreement with the opinion that all women should be offered hysteroscopy, even if they have normal vaginal ultrasound and hysterosalpingography, because this is supposed to increase the detection rate of minor abnormalities, which theoretically will improve the reproductive outcome. Still, further interventional randomized controlled trials (RCT) are needed to verify the positive impact of routine use of hysteroscopy prior to ART

Indications et aspects histopathologiques des biopsies de l'endometre a l'Hopital Gyneco-Obstetrique et Pediatrique de Yaoundé (Cameroun)

Une étude rétrospective et descriptive de 118 biopsies endo-métriales a été effectuée à l'Hôpital Gynéco-Obstétrique et Pédiatrique de Yaoundé pour répertorier les indications et les aspects histologiques. Résultats. L'âge moyen était de 46,85 ±13,57 ans. Les saignements utérins anormaux et l'hydrorrhée vaginale constituaient les indications les plus fréquentes (84,76% et 8,47% respectivement). Le mode de prélèvement le plus utilisé était le curetage biopsique (91,5%). Les lésions histologiques étaient dysfonctionnelles (79,66%), cancéreuses(13,56%) et inflammatoires (6,78%). Les cancers les plus fréquentes étaient l'adénocarcinome endométrial invasif (50,0%) et le carcinome épidermoïde invasif (25,0%); Certains de ces cancers étaient probablement d'origine cervicale. Les lésions dysfonctionnelles (69,49%)et cancéreuses (13,55%) étaient statistiquement associées aux saignements utérins anormaux et les lésions inflammatoires (3,38%) à l'hy-drorrhée vaginale. Conclusion. Les lésions dysfonctionnelles occupent une place plus importante chez les femmes en période d'activité géni-tale et devraient être pris en compte dans la mise en place des algo-rithmes de prise en charge de la pathologie endométriale

Endometrial Pathology in a Teaching Hospital in North-Central Nigeria - A Histopathological Survey

The study was a 5 year histopathological survey of endometrial biopsies seen at the University of Ilorin Teaching Hospital ; Ilorin; North Central Nigeria from January 1st 1997 to December 31st 2001. It aimed at identifying the morphological patterns of endometrial disorders; prevalence of these disorders and the histopathological changes associated with the clinical diagnosis in Ilorin; Nigeria. Eight hundred and eighty two slides of cases of endometrial disorders recorded in the register of the Department of Pathology; University of Ilorin Teaching Hospital; Ilorin; North Central Nigeria were reviewed. Clinical data on each of the cases was retrieved from request cards. The pathological reports and clinical data were recorded noting the age; clinical history; morphological description of lesions and the histological types. The mean age of the studied group was 28 years. The commonest indication for endometrial sampling was infertility (55.3