Cutaneous leishmaniasis in Sudan: an update

Cutaneous leishmaniasis due to L.major is now endemic in many parts of the northern Sudan. In this up-date we discuss the clinical manifestations of cutaneous leishmaniasis; its diagnosis and treatment. The most common clinical forms are nodular; noduloulcerative and ulcerative lesions. Less common forms are sporotrichoid lesions; leishmanial dactylitis; leishmanial cheilitis; mycetoma- and residivans-like types. In a suspected case the diagnosis is made by demonstration of leishmania parasites in slit smears or biopsy; isolation of the parasite by culture in appropriate media and by the polymerase chain reaction (PCR) using specific primers. The majority of lesions heal spontaneously. Criteria for local or systemic treatment are given