RESUMO
Background: Iron and folic acid supplementation plays a major role in the prevention and control of iron-deficiency anaemia in pregnancy. Therefore, this study assesses adherence to prophylactic iron supplementation during the antenatal period in South Africa. Methods: An observational study was conducted in a regional hospital from January to December 2016. HIV-uninfected(n= 100) and HIV-infected (n= 100)] women were enrolled and subdivided into three groups: (a)â¤34 weeks (n= 33), (b)3436 weeks (n= 34) and (c)â¥37 weeks (n= 33) gestational age respectively. A structured questionnaire was used for data collection. Data were coded and statistically analysed using SPSS software. Pill count and self-reported data from women (n= 24) atâ¤34 weeks and 3436 weeks reflected < 50% adherence and 46% non-adherence, being higher in the HIV-infected women (75%). Nausea was the commonest side effect across all trimesters (79. 2%). Adherence (27.8%) and non-adherence (72.1%) to iron, folic acid and calcium supplementation were found in 88% of women. Conclusion: This study found that adherence to micronutrient supplementation is low in pregnancy, albeit higher in HIV-infected women receiving antenatal care at a regional hospital in Durban, South Africa
Assuntos
Anemia , Anemia Ferropriva , Hospitais , Gravidez , Reticulócitos , África do SulRESUMO
Background. The diagnosis of iron deficiency (ID) and iron-deficiency anaemia (IDA) in ill children is complicated by the unreliability of serum ferritin (S-ferritin). The presence of a microcytic; hypochromic anaemia suggests IDA but is not specific. There is a need for a diagnostic test that will be accessible; cost-effective and accurate for the diagnosis of ID in ill children. Studies done in healthy children have reported that reticulocyte haemoglobin content (CHr) is a reliable diagnostic test for ID; eliminating the need for S-ferritin determination.Objective. To evaluate the accuracy of CHr to diagnose ID and IDA in ill infants and children.Methods. A prospective; descriptive study was conducted. One hundred children; aged 6 months to 6 years; who were admitted to Pelonomi Regional Hospital; Bloemfontein; South Africa; during July 2012 and August 2012 were included. Results. The study group was divided into an iron-deficient group and an iron-sufficient group based on transferrin saturation (TfS). A statistically significant difference was found between mean corpuscular haemoglobin (MCH); serum transferrin and CHr in these two groups (p=0.0001). The sensitivity of a CHr level ?29 pg to detect ID was 86; and the specificity was 50. Conclusion. CHr is an accurate diagnostic test for ID; and for IDA in combination with a low haemoglobin level; in ill infants and children
Assuntos
Anemia , Criança , Ferritinas , Lactente , ReticulócitosRESUMO
Background: In this study; the effect of cold and haemorrhagic stressors in male albino Wistar rats will be investigated. Methods: Cold stress was induced by placing the animals in thermostatic chamber containing ice cold water (0-10oC) and well aerated. Rats were allowed to stay for 5; 10; 15 and 20 minutes before they were bled from the tail vein at 2; 4; 6; 8 and 24 hours for reticulocyte counts. For the haemorrhagic stress; 30of blood was withdrawn from the vein after which reticulocytes were counted at 2; 4; 6; 8 and 24 hours. Results: Cold and haemorrhagic stress caused increased reticulocyte counts in male albino Wistar rats. The controls were not subjected to any condition. In cold stress; the maximum percentage reticulocyte count was (at zero hour) 6.21 + 0.21while the control was 1.02 + 0.12. In the case of the haemorrhagic stressor; the percentage reticulocyte was seen to peak at the 6th hour (6.19 + 0.12) and subsequently decrease to 2.59 + 0.02. The probable causes of this rise in reticulocytes are discussed. Conclusion: In cold and haemorrhagic stress; reticulocyte count peaked at 2 and 6 hours respectively; depicting when maximum erythropoietic activity was reached in blood forming organs
Assuntos
Hemorragia , Ratos Wistar , Reticulócitos , Estresse FisiológicoRESUMO
Cette etude rapporte les valeurs reticulocytaires (0;1 - 1 pour cent; soit 4220 - 49.900/mm3) chez 54 enfants de 3 a 14 ans dont 34 garcons et 20 filles; tous scolaries; en bonne sante apparente et vivant a Abidjan. Ces valeurs refletent une hypo-activite medullaire qui pourrait etre rattachee au status alimentaire precaire des enfants des pays en voie de developpement
Assuntos
Serviços de Saúde da Criança , Países em Desenvolvimento , Estado Nutricional , ReticulócitosRESUMO
Sickle cell anaemia patients in steady state have haematological values different from the normal population. Sickle cell patients are in a steady state when they are not in crisis and have no bacterial infection. The haemoglobin level is low and reticulocyte count high. There is also peripheral leucotosis and thrombocytosis