Iron overload and pregnancy outcome among Sudanese women

Dispensing iron tablets to pregnant women at antenatal clinics is a common practice in Sudan.Iron overload and; consequently; oxidative stress is a possible risk.Objective: In this study; we examined the iron status in pregnant women in correlation to pregnancy outcome.Subjects and methods: The study was conducted in Khartoum state; Sudan in the period December 2007 February 2009. Venous blood samples were obtained from 123 women at delivery.Undesirable pregnancy outcomes as preeclampsia; low birth weight; caesarean sections and preterm delivery; if any; were recorded. Serum iron and hematological parameters were determined.Results: Mothers were grouped; according to their serum iron levels; as low serum iron (LSI: 50 7g/dl; n170 7g/dl;n=11) groups. The incidence of preeclampsia was highest among the IOL group (72.7); followed by the LSI group (35.7) and lowest among the NSI (19.4) group; p=. The mean babies' birth weights were comparable among the IOL and the LSI groups but both were significantly lower than that among the NSI group.Conclusion: Iron supplementation to pregnant women must be rationalized so that women will benefit without developing undesirable effects

Effect of Traditional Beer Consumption on the Iron Status of A Rural South African Population

Objective.To determine the effect of traditional beer consumption on the iron status of rural black subjects.Design. A cross-sectional study was undertaken.Setting. Dikgale field site and the surrounding villages in Limpopo Province; South Africa.Subjects. Eight hundred and forty-four non-alcohol consumers (738 women and 106 men) and 280 alcohol consumers (163 women and 117 men) aged 30 years and above; participated in the study.Outcome measures. Outcome measures included alcohol consumption; serum ferritin levels; percentagetransferrin saturation; total iron-binding capacity; haemoglobin and C-reactive protein levels.Results. Traditional beer fermented in either iron pots or plastic containers was found to have iron levels ranging from 15 mg/l to 67.8 mg/l and 6 mg/l to 17 mg/l; respectively. Iron status as measured by serum ferritin; serum iron; percentage transferrin saturation; and haemoglobin levels was significantly higher in alcohol consumers than in non-consumers; even after adjustment for age and C-reactive protein (CRP) levels. A high percentage of women (12.3) and men (8.2) consuming alcohol had iron overload.Conclusion. This study showed that consumption of traditional beer in a non-urban population in Limpopo Province was associated with high levels of markers of iron status. Traditional beer consumption seemed to prevent iron deficiency in those at risk of developing such deficiency; but appeared to precipitate iron overload in those at risk of developing iron overload