Genital Mycoplasmas in Women Attending the Yaounde University Teaching Hospital in Cameroon

Genital mycoplasmas are implicated in pelvic inflammatory diseases; puerperal infection; septic abortions; low birth weight; nongonococcal urethritis and prostatitis as well as spontaneous abortion and infertility in women. There is paucity of data on colonisation of genital mycoplasma in women and their drug sensitivity patterns. The aim of our study was to determine the prevalence of genital mycoplasmas (Ureaplasma urealiticum and Mycoplasma hominis) infection and their drug sensitivity patterns in women. A mycofast kit was used for biochemical determination of mycoplasma infection in 100 randomly selected female patients aged 19-57 years; attending the University of Yaounde Teaching Hospital (UYTH) from March to June 2010. Informed consent was sought and gained before samples were collected. Genital mycoplasmas were found in 65 patients (65) [95CI=55.7-74.3] and distributed as 41 (41) [95CI=31.4-50.6] for U. urealiticum and 4 (4) [95CI=0.20-7.8] for M. hominis while there was co-infection in 20 women (20) [95CI=12.16-27.84]. In our study; 57 (57) [95CI=47.3- 67] had other organisms; which included C. albicans (19 [19]); G. vaginalis (35 [35]) and T. vaginalis (3 [3]). Among the 65 women with genital mycoplasma; the highest co-infection was with G. vaginalis (33.8). Pristinamycine was the most effective antibiotic (92) and sulfamethoxazole the most resistant (8) antibiotic to genital mycoplasmas. We concluded that genital mycoplasma is a problem in Cameroon and infected women should be treated together with their partners

In Vitro Activity of Medicinal Plants of the Venda region; South Africa; against Trichomonas vaginalis

Trichomonas vaginalis is an important and common cause of urogenital infections in both developed and in developing countries. In view of the high prevalence; increase in resistance to drug therapy and associated risk of acquisition and transmission of HIV; we screened the aqueous extracts of 29 plants. These plants are used to treat venereal diseases and infections in the Venda region. Extracts of four plants showed trichomonicidal activity: Securidaca longepedunculata Fresen. (Polygalaceae; 0.10 mg/ml); Solanum aculeastrum Dun. (Solanaceae; 1.06 mg/ml); Piper capense L.f. (Piperaceae; 11.19 mg/ml) and Cassine transvaalensis (Burtt. Davy) Codd (Celastraceae; 9.69 mg/ml). Further investigations are required to determine whether these plants possess the potential to be developed as new drugs for the treatment of trichomoniasis

Evaluation technique du diagnostic biologique de l'écoulement génital chez l'homme dans un laboratoire de 3eme niveau de 2001 à 2002

SANS RESUME

Diagnosis of Vaginal Infection in Pregnancy

Pregnant women are prone to vaginal infection. At Primary Health Care Clinics diagnosis of causative organism of vaginal infections is made by using history-taking and assessment of clinical picture methods. The accuracy of these methods is investigated in this stctdy by comparing the results obtained by history taking and assessment of clinical picture with that which is obtained by examining wet mount specimens under a microscope. Seventy respondents participated in the study Irz 48; 6 cases; the diagnosis of causative organism; as identified by the two different methods; were similar. In 51.4 of the cases the diagnosis differed Candida albicans infection was diagnosed by 10 respondents; while 3 actlrally had Trichomonas vaginalis infection and seven had Gardnerella vaginalis infection. Trichomomonas vaginalis infection was diagnosed in 26 cases; while 15 were actually due to Candida albicans and 11 due to Gardnerella vaginalis

Culture Polyxenique d'Entamoeba histolytica; de Trichomonas vaginalis; et de Trichomonas hominis sur milieu de Dobell-Laidlow modifie

Le milieu Dobell-Laidlow; mis au point en 1926 par les auteurs dont le nom; s'avere; du fait de sa simplicite; le plus efficace; pour l'isolement; l'entretien de longue duree; des souches d'Entomoeba histolytica; la production de l'antigene utilise dans les tests d'immunofluorescence indirecte pour le diagnostic de l'amibiase tissulaire; et les essais pharmacologiques des plantes medicinales presumees amoebicides. En operant la substitution du serum de cheval qui entre traditionnellement dans sa preparation par du serum de vache; animal plus familier; les auteurs ont facilite significativement la procedure de sa preparation. D'autre part; le succes obtenu dans les essais de culture de Trichomonas vaginilis; d'une part ; et celle de Trichomonas hominis; d'autre part; sur ce meme milieu; vient d'etendre le spectre des protozoaires susceptibles de pousser desus