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Lactate clearance predicts outcome after major trauma
Heinonen, Essi; Hardcastle, Timothy Craig; Barle, Hans; Muckart, David James Jackson.
  • Heinonen, Essi; s.af
  • Hardcastle, Timothy Craig; s.af
  • Barle, Hans; s.af
  • Muckart, David James Jackson; s.af
Artigo em Inglês | AIM | ID: biblio-1258644
Biblioteca responsável: CG1.1
ABSTRACT

Introduction:

To determine a correlation between lactate clearance within 48h and survival in trauma patients at a Level I trauma centre in a developing country and compare to previous international lactate clearance studies.

Methods:

We conducted a retrospective study of a prospectively collected database at a Level I trauma centre from March 2007 to November 2010. Patients of all ages were included. Metabolic parameters from initial arterial blood gas were measured in all patients; an abnormal lactate beindefined as 2.5mmol/L. A subgroup analysis of blunt versus penetrating injury was performed.

Results:

Of the 657 patients in the database; 493 had complete lactate data. The survival rate of patients with lactate values 2.5mmol/L was 88. Of the patients with high lactate levels that cleared within 24 and 48h the survival rates were 81 and 71; respectively. The survival rate amongst patients not achieving a normal lactate within 48h was 46 but was higher in those with penetrating as opposed to blunt injury (67 versus 38). The overall survival was 81.

Conclusion:

The present results confirm previous studies showing that prolonged lactate clearance predicts increased mortality in severely injured trauma patients. Thus; the measurements of arterial serum lactate trends are simple and effective predictors of

outcome:

Assuntos
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Índice: AIM (África) Assunto principal: Sobrevida / Ferimentos e Lesões / Ácido Láctico / Serviços Médicos de Emergência / Unidades de Terapia Intensiva Tipo de estudo: Estudo observacional / Estudo prognóstico / Fatores de risco Idioma: Inglês Revista: African journal of emergency medicine (Print) Ano de publicação: 2014 Tipo de documento: Artigo

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Índice: AIM (África) Assunto principal: Sobrevida / Ferimentos e Lesões / Ácido Láctico / Serviços Médicos de Emergência / Unidades de Terapia Intensiva Tipo de estudo: Estudo observacional / Estudo prognóstico / Fatores de risco Idioma: Inglês Revista: African journal of emergency medicine (Print) Ano de publicação: 2014 Tipo de documento: Artigo