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Plasma Concentration of Ascorbic Acid and Some Hematological Parameters in Tobacco Snuffers Among the Igbos of Southeastern Nigeria
Ureme, S. O; Njoku, O. U; Ejezie, F. E; Ibeh, B. O; Ikekpazu, E; Mba, M. J.
  • Ureme, S. O; s.af
  • Njoku, O. U; s.af
  • Ejezie, F. E; s.af
  • Ibeh, B. O; s.af
  • Ikekpazu, E; s.af
  • Mba, M. J; s.af
Artigo em Inglês | AIM | ID: biblio-1259222
Biblioteca responsável: CG1.1
RESUMO
Tobacco snuffing; like cigarette smoking; is known to be a common habit among the adults of Igbo communities in Nigeria. In view of the various pharmacological actions of nicotine and other additive constituents of tobacco snuff; there is growing concern that ascorbic acid; which is a vital antioxidant; and blood cell production or morphology may be affected.

Objective:

To investigate the possible effects of prolonged use of tobacco snuff on plasma ascorbic acid concentrations and some hematological parameters. Materials and

Methods:

Fifty adults of Igbo extraction (35 males and 15 females) residents in and around Enugu metropolis; who have been snuffing tobacco for 6 years and above; were recruited for the study; after they gave informed consent. Also; 50 apparently healthy; age-matched persons (25 males; 25 females); who do not smoke or take tobacco snuff; served as controls. Spectrophotometric method was adopted for ascorbic acid determination while hematological profiles were assessed by Bain method.

Results:

The results showed no significant difference in the measured parameters relative to the controls AA (P=0.08); Hb (P=0.19); PCV (P=0.10); RC (P=0.06); PC (P=0.20); WBC (P=0.09).

Conclusion:

The results of the study suggest that tobacco snuff inhalation may not adversely affect plasma ascorbic acid concentration and hematological parameters in adult humans. The study; however; has not concluded that tobacco snuffing is totally wholesome
Assuntos
Texto completo: DisponíveL Índice: AIM (África) Assunto principal: Intoxicação por Plantas / População Rural / Nicotiana / Ácidos / Neoplasias Bucais / Lagos / Estresse Oxidativo / Ações Farmacológicas / Lobelina / Nigéria País/Região como assunto: África Idioma: Inglês Revista: Ann. med. health sci. res. (Online) Ano de publicação: 2012 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: AIM (África) Assunto principal: Intoxicação por Plantas / População Rural / Nicotiana / Ácidos / Neoplasias Bucais / Lagos / Estresse Oxidativo / Ações Farmacológicas / Lobelina / Nigéria País/Região como assunto: África Idioma: Inglês Revista: Ann. med. health sci. res. (Online) Ano de publicação: 2012 Tipo de documento: Artigo