Disorders of Sexual Differentiation as seen at Kenyatta National Hospital
East Afr. Med. J
; 93(1): 10-14, 2016.
Artigo
em Inglês
| AIM
| ID: biblio-1261399
Biblioteca responsável:
CG1.1
ABSTRACT
Background:
Disorders of sexual differentiation (DSD) are a group of congenital anomalies characterised by discordance between genetic; gonadal and phenotypic sex. There has been remarkable evolution in management over the last decade; including nomenclature; diagnosis and management. There has also been increased awareness and interest from patients and the public; including legal opinion. There has however been no local study to document and evaluate management in Kenya.Objective:
To describe management of patients presenting with DSD at Kenyatta National Hospital (KNH) over a 10 year period.Design:
Retrospective descriptive study.Setting:
Kenyatta National Hospital.Subjects:
Patients diagnosed with DSD.Results:
A total of 30 patients whose charts were available were reviewed. Age ranged from birth to 19 years (median 5 months) at diagnosis. Presumed gender was assigned at birth in 28 patients. Karyotyping was available in 23(76%) patients. Other common tests included blood tests (23; 76%); ultrasound scan (14; 47%); contrast studies (3; 10%) and exploratory laparoscopy or laparotomy. 46XX and 46XY DSD were the most common conditions encountered (13; 43% and 7; 23% respectively). The commonest operations were correction of hypospadias and orchidopexy (55%); followed by feminising genitoplasty (16%). Only two patients had gender reassignment. Fifteen patients were asked how they feel about their current gender; and 11 expressed satisfaction.Conclusion:
DSD is a relatively rare condition. There are also no strict protocols being followed. Management at KNH is acceptable although there is a lack of facilities to carry out many requisite investigations
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Índice:
AIM (África)
Assunto principal:
Diferenciação Sexual
/
Transtornos do Desenvolvimento Sexual
/
Gerenciamento Clínico
/
Hospitais
Tipo de estudo:
Guia de Prática Clínica
Idioma:
Inglês
Revista:
East Afr. Med. J
Ano de publicação:
2016
Tipo de documento:
Artigo
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