Causes of Death in Hospitalized HIV Patients in the Early Anti-Retroviral Therapy Era
Ghana Med. J. (Online)
; 49(1): 7-11, 2014.
Artigo
em Inglês
| AIM
| ID: biblio-1262286
Biblioteca responsável:
CG1.1
ABSTRACT
Objective:
To establish the cause(s) of death among persons with HIV and AIDS admitted to the Fevers Unit of the Korle-Bu Teaching Hospital (KBTH) in 2007 and to determine whether they were AIDS-relatedin the era of availability of HAARTMethod:
Retrospective chart review of all deaths that occurred in the year 2007 among inpatients with HIV infection. Cause of Death (COD) was established with post mortem diagnosis; where not available ICD-10 was reviewed independently by two physicians experienced in HIV medicine and a consensus reached as to the most likely COD.Results:
In the year under review; 215 (97) of the 221 adult deaths studied were caused by AIDS and HIV-associated illnesses. Of these; 123 (55.7) were due to an AIDS-defining illness as described in CDC Category 3 or WHO stage 4. Infections accounted for most of the deaths 158 (71.5); many of them opportunistic 82 (51.8). Tuberculosis was the commonest COD. Clinical diagnosis of TB was accurate in 54 of deaths; but was not validated by autopsy in 36 of deaths. There were few deaths (14.5) in patients on HAART.Conclusion:
In a developing country like Ghana where HAART was still not fully accessible; AIDS-related events remained the major causes of death in persons living with HIV. Total scale-up of the ART programme with continuous availability of antiretrovirals is therefore imperative to reduce deaths from AIDS and HIV associated illnesses. There is need for interventions for early diagnosis as well as reduction in late presentation and also better diagnostic tools for tuberculosis
Texto completo:
DisponíveL
Índice:
AIM (África)
Assunto principal:
Infecções por HIV
/
Causas de Morte
/
Infecções Oportunistas Relacionadas com a AIDS
/
Pacientes Internados
Tipo de estudo:
Estudo de etiologia
/
Estudo de rastreamento
Idioma:
Inglês
Revista:
Ghana Med. J. (Online)
Ano de publicação:
2014
Tipo de documento:
Artigo
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