The Antibiotic Susceptibility of Bacteria Isolated from Blood Cultures during Episodes of Neutropenic Fever in Patients with Acute Myeloid Leukaemia
S. Afr. j. infect. dis. (Online)
; 25(2): 9-11, 2010.
Artigo
em Inglês
| AIM
| ID: biblio-1270624
Biblioteca responsável:
CG1.1
ABSTRACT
Neutropenic fever (NF) is a common and life-threatening complication of high-dose chemotherapy in patients with acute myeloid leukaemia (AML). Induction chemotherapy may result in complete remission in approximately 50-70of AML patients but is associated with an increased risk of infection due to immune suppression by the disease itself or as a result of treatment. Chemotherapy causes neutropenia as well as defective chemotaxis and phagocytosis. Chemotherapy-induced mucositis often occurs throughout the gastrointestinal tract; facilitating spread of endogenous flora to the blood circulation; leading to NF. The aim of this study was to determine the spectrum of bacteraemic microorganisms isolated during episodes of NF (NFEs) in AML patients in the Haematology Unit of the Universitas Academic Complex (UAC); as well as antibiotic susceptibility profiles of these organisms. Duration of NF; the time-span between chemotherapy and onset of NF; and the efficacy of antibiotics administered to patients; were also investigated
Texto completo:
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Índice:
AIM (África)
Assunto principal:
Bactérias
/
Leucemia
/
Testes de Sensibilidade Microbiana
/
Antibioticoprofilaxia
/
Febre
/
Neutropenia
Idioma:
Inglês
Revista:
S. Afr. j. infect. dis. (Online)
Ano de publicação:
2010
Tipo de documento:
Artigo
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