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The Initiation of Anti-retrovirals in Critically Ill Patients
Venturas, Jacqueline P.
  • Venturas, Jacqueline P; s.af
Artigo em Inglês | AIM | ID: biblio-1270680
Biblioteca responsável: CG1.1
ABSTRACT
The initiation of anti-retrovirals in critically ill patients is complicated. Although there are no prospective trials that address this issue; retrospective studies suggest that early initiation of treatment in these patients is probably beneficial. Hesitance to use these drugs in an intensive care population stems from problems related to anti-retroviral administration; toxicities; drug interactions; altered pharmacokinetics of the drugs and the immune reconstitution inflammatory syndrome (IRIS). In addition to this; critically ill patients are often unable to give informed consent for HIV testing; or undergo appropriate counseling; which raises ethical problems; as well as problems related to long-term compliance. This article summarizes the evidence available for the early initiation of anti-retrovirals in critically ill patients; as well as problems related to their administration
Assuntos
Texto completo: DisponíveL Índice: AIM (África) Assunto principal: Pacientes / Terapêutica / Infecções por HIV / Cuidados Críticos / Antirretrovirais / Ética Tipo de estudo: Estudo observacional Idioma: Inglês Revista: S. Afr. j. infect. dis. (Online) Ano de publicação: 2012 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: AIM (África) Assunto principal: Pacientes / Terapêutica / Infecções por HIV / Cuidados Críticos / Antirretrovirais / Ética Tipo de estudo: Estudo observacional Idioma: Inglês Revista: S. Afr. j. infect. dis. (Online) Ano de publicação: 2012 Tipo de documento: Artigo