Pharmacokinetics and tissue responsiveness in neonates

ABSTRACT

"Neonates and infants are not just ""little humans"". Pharmacologically and in therapeutic considerations; empirical rules for dosage adjustments for children are still useful guidelines; but; sometimes; it is equally important to take other factors besides age; body weight; and body surface areas; (namely pharmacokinetic parameters; drug intake via breast milk; and tissue responsiveness) into account for fixing drug doses for the neonates."