An audit of CT brain findings in adults with new-onset seizures in a resource restricted setting in South Africa
SA j. radiol
; 26(1): 1-7, 2022.
Artigo
em Inglês
| AIM
| ID: biblio-1354430
Biblioteca responsável:
CG1.1
ABSTRACT
Background:
Globally, adults presenting with seizures account for 1% 2% of visits to emergency departments (EDs), of which 25% are new-onset seizures. Neuroimaging is essential as part of the initial workup. Multiple studies have demonstrated abnormal CT brain (CTB) findings in these patients.Objectives:
To review the CTB findings in adults presenting with new-onset seizures in a resource restricted setting.Method:
A retrospective review of 531 CTBs was conducted at a tertiary hospital in Gauteng on adults presenting to the ED with new-onset seizures.Results:
The mean age of the patients was 45.6 ± 17.1 years, and the male to female ratio was 1.21. Generalised and focal seizure types were almost equally represented. Of the total 531 patients, 168 (31.6%) were HIV positive. The CTB findings were abnormal in 257 (48.4%) patients, albeit vascular pathology accounted for 21.9%. Infective pathology accounted for 14.1% with a statistically significant association with HIV (p = 0.003). Trauma related pathology was 2.4%, whilst neoplastic pathology was seen in 3.0%. Other causes included congenital pathology, calcifications, atrophy and gliosis. Clinical factors associated with abnormal CTB findings were age ≥ 40 years, HIV infection, hypertension, focal seizures, low Glasgow Coma Scale (GCS), raised cerebrospinal fluid (CSF) protein and presence of lymphocytes.Conclusion:
A high yield of abnormal CTB findings was noted in adult patients who presented with new-onset seizures, supporting the use of urgent CTB in patients with certain clinical risk factors. Patients without these risk factors can be scanned within 2448 h in a resource restricted setting.
Texto completo:
DisponíveL
Índice:
AIM (África)
Assunto principal:
Convulsões
/
Encéfalo
/
Auditoria Médica
Tipo de estudo:
Fatores de risco
Limite:
Adulto
/
Humanos
Idioma:
Inglês
Revista:
SA j. radiol
Ano de publicação:
2022
Tipo de documento:
Artigo
Instituição/País de afiliação:
Department of Radiology, Faculty of Health Sciences, Chris Hani Baragwanath Hospital, University of the Witwatersrand/ZA
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