Short-term outcomes among patients with subclinical hypothyroidism undergoing primary percutaneous coronary intervention
Ghana med. j
; 57(1): 37-42, 2023. figures, tables
Artigo
em Inglês
| AIM
| ID: biblio-1427100
Biblioteca responsável:
CG1.1
ABSTRACT
Objectives:
This study aimed to examine possible associations between previously undiagnosed subclinical hypothyroidism and short-term outcomes and mortality in a sample of Iraqi patients undergoing primary percutaneous coronary intervention for ST-segment elevation myocardial infarction.Design:
This is a prospective observational cohort study.Setting:
The study was conducted in a single tertiary referral centre in Baghdad, Iraq.Participants:
Thyroid-stimulating hormone and free T4 levels were measured in 257 patients hospitalised with STelevation myocardial infarction who underwent primary percutaneous coronary intervention between January 2020 and March 2022. Main outcomemeasures:
Adverse cardiovascular and renal events during hospitalisation and 30-day mortality were observed.Results:
Previously undiagnosed subclinical hypothyroidism was detected in 36/257 (14%) ST-elevation myocardial infarction patients and observed more commonly in females than males. Patients with subclinical hypothyroidism had significantly worse short-term outcomes, including higher rates of suboptimal TIMI Flow (< III) (p =0.014), left ventricular ejection fraction ≤ 40% (p=0.035), Killip class >I (p=0.042), cardiogenic shock (p =0.016), cardiac arrest in the hospital (p= 0.01), and acute kidney injury (p= 0.044). Additionally, 30-day mortality was significantly higher in patients with subclinical hypothyroidism (p= 0.029).Conclusion:
Subclinical hypothyroidism previously undiagnosed and untreated had a significant association with adverse short-term outcomes and higher short-term mortality within 30 days compared to euthyroid patients undergoing primary percutaneous coronary intervention. Routine thyroid function testing during these patients' hospitalisation may be warranted.
Texto completo
- https://www.ghanamedj.org/articles/March2023/6_Short-term%20outcomes%20among%20patients%20with%20subclinical%20hypothyroidism%20undergoing%20primary%20pci.pdf
- https://indexmedicus.afro.who.int/iah/fulltext/Short-term outcomes among patients with subclinical hypothyroidism undergoing primary percutaneous coronary intervention.pdf
- https://fi-admin.bvsalud.org/document/view/4pjzh
Texto completo:
DisponíveL
Índice:
AIM (África)
Assunto principal:
Testes de Função Tireóidea
/
Intervenção Coronária Percutânea
/
Hipotireoidismo
Tipo de estudo:
Estudo observacional
/
Fatores de risco
Limite:
Humanos
Idioma:
Inglês
Revista:
Ghana med. j
Ano de publicação:
2023
Tipo de documento:
Artigo
Instituição/País de afiliação:
Department of Medicine, College of Medicine, al-Mustansiriyah University/IQ
/
Department of Obstetrics and Gynecology, College of Medicine, al-Nahrain University/IQ
/
Department of Pediatrics, College of Medicine, al-Mustansiriyah University/IQ
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