ABSTRACT
Background and Objective: Varicella zoster virus [VZV] can cause a moderate disease in children, but with high risk of serious disease or death in children with acute lymphoblastic leukemia [ALL] Vaccination from infection can be safe, immunogenic, and effective in children with leukemia. This study was done to evaluate the IgG and IgM antibodies against VZV in children with acute lymphoblastic leukemia
Methods: The descriptive-analytic study was performed on 66 children who were on chemotherapy in Dr Shigh hospital in Mashhad, Iran during 2012. Patients were receivied VZV vaccine. The title negative or positive serum sample for IgG-anti-VZV avidity was determined by using a test kit before and after injection of vaccines VZV for considering the efficacy of vaccines on pediatric patients
Results: Title serum sample IgG were positive in 32.6% patients, these children have history of chicken pox disease and to be safe against of VZV. 78.3% of the patients were negative for IgG antibody and sensitive against of VZV
Conclusion: Children with ALL receiving chemotherapy are sensitive to chicken pox disease according to negative IgG titer against VZV
Subject(s)
Humans , Female , Male , Carcinoma, Hepatocellular/diagnosis , Immunohistochemistry , Liver/pathology , Liver Diseases/diagnosis , Antigens, CD34ABSTRACT
Sinus histiocytosis with massive lymphadenopathy [SHML] or Rosai-Dorfman disease [RDD] is a rare benign histiocytic disease of unknown etiology, usually associated with lymph node enlargement in various superficial or deep sites. It usually shows a prolonged clinical course with occasional exacerbation and remission phases. In this article case of RDD in a 5-year-old male with large right inguinal and bilateral cervical lymphadenopathies were, occasional fever and anemia was described. The clinical presentation, histopathologic characteristics, and treatments of RDD were discussed
ABSTRACT
To compare the frequency of Helicobacter pylori [H. pylori] infection in subjects with primary open angle glaucoma [POAG] vs controls. In a case-control study, 44 patients with primary open angle glaucoma and 79 patients with senile cataract [control group] were investigated for serum level of anti-H. pylori antibody using the enzyme-linked immunosorbant assay [ELISA] method. The study included 26 male and 18 female subjects with mean age of 60.8 +/- 20.6 years in the case group and 44 male and 35 female subjects with mean age of 66.0 +/- 19.8 years in the control group. Seropositivity was higher in patients with glaucoma [70.5%] compared to controls [40.5%] with an odds ratio of 3.51 [95% confidence interval, 2.89-4.11; P= 0.001]. H. pylori infection is much more prevalent in patients with primary open angle glaucoma. Further investigations are required to evaluate the possible causative role of H. pylori infection in primary open angle glaucoma
ABSTRACT
Ntestinal endometriosis is a rare but clinicaly significant complication. The most commonlly involved sites are the rectosigmoid and rectovaginal septum. Although serosal involvement is not uncommon in women of child bearing age. The mucosal involvement is rare and differential diagnosis from colon cancer may be difficult due to the lack of pathogonomonic symptoms and the poor diagnostic yield of colonoscopy and colonic biopsies. We present a case of a 31-year young woman with sigmoid endometriosis is presented with rectal bleeding in which the initial diagnostic workup suggested colon cancer. Histological evidence obtained from a colonoscopy along with clinical history Led to the final diagnosis of intestinal endometriosis