ABSTRACT
Portulaca oleracea [PO] and Melissa officinalis [MO] overgrow in the different parts of Iran. In previous studies, systemic administration of the extracts of PO and MO induces antinociceptive, anxiolytic and anticonvulsive, sedative effects in animals. This study was designed to evaluate different doses of the aqueous decoction extracts of PO and MO on sleeping time on mice. Male albino mice [25-30 g] were used in this study. The animals divided to control [saline], PO [25, 50 and 75 mg/kg] and MO [5, 10 and 25 mg/kg] groups [by IP injection]. For measuring of sleeping time we used Angle method. The results have shown that three doses of PO and two doses of 10 and 25 MO significantly increased sleeping time [p=0.000]. This finding showed that PO and MO may be play important role on the modulation of sleeping time
ABSTRACT
Obesity has been known as a risk factor in cardiovascular disease. Educational intervention aimed at modifying dietary habits and physical activity patterns are essential in management of obesity. The purpose of this study was to compare the effects of family-based intervention and individualbased intervention on body mass index and life style. This quasi-experimental study was conducted on subjects suffering from obesity or overweight in Islam-Abad, Zanjan [2005-2006]. The subjects were assigned nonrandomly to either the family-based group [n=42] or individual-based group [n=49]. Data were collected using a questionnaire. Intervention included counseling to make change, in eating habit and exercise behavior. Subjects in the individual-based group received intervention individually in the clinics, and those in the family-based intervention received intervention by home visit. The data were analyzed using Chi-square test, T-test, Paired T-test, Mann-Whitney test and, Wilcoxon test. The mean of body mass index decreased from 30.74 +/- 3.99 to 30.1 +/- 3.90 and from 31.98 +/- 6.64 to 31.57 +/- 6.63 in family-based group and in individual-based group, respectively. After intervention, the mean of body mass index significantly decreased in both groups [p < 0.05]. There was no significant difference in body mass index between two groups after intervention [P=0.52]. The mean scores of dairy product consumption and fruit consumption as well as physical activity were increased in both groups [p < 0.0001]. It was concluded that both family-based and individual -based intervention, focusing on physical activity and diet counseling through regular follow-up meetings, could be effective ways of controlling CVD risk factors