ABSTRACT
Research and development of potent and effective antimicrobial agents represent one of the most important advances in therapeutics; the main aim of these efforts is not only control the serious infections, but also prevention and treatment of some infectious complications of other therapeutic modalities. A series of 5-(2- aroyl)aryloxy methyl-2-phenyl-1,3,4-oxadiazoles were screened for their antibacterial and antifungal activities. Anti-bacterial activity against B. cereus, S. aureus, B. subtilis, S. aureus (MRSA), E. aerogenes, M. luteus, K. pneumonia, P. aeruginosa, S. typhimurium, E. coli, paratyphi-B, P. vulgaris bacterial strains and anti-fungal activity against C. albicans, A.niger, F.solani, A.flavus, B.cinerea, C.krusei, M. pachydermatis, C.parapsilosis, F.moniliforme, C.gloeosporioides fungal strains were carried out. The bioassays indicated that most of the synthesized compounds showed potential antibacterial and anti-fungal activity.
ABSTRACT
A study of 351 patients of lymphadenopathy was carried out to observe the pattern of various diseases with which these patients were affected. There were 168 male and 183 female patients with male to female ratio of 1:1.09. The youngest patient was 1 year old and the oldest was 80 years of age. The commonest lesion found was tuberculosis in 165 [47%] followed by reactive hyperplasia in 121 [34.5%], metastatic carcinoma in 36 cases [10.3%], malignant lymphoma in 27 cases [7.7%], kikuchi's lymphadenitis in one case [0.28%], and fungal lymphadenitis in one [0.28%]