ABSTRACT
In order to know the Cassia Angustifolia [Senna] leaves effect on the blood pressure and pulse rate, three clinical trials were carried out on thirty Yemeni male patients with mild hypertension. In the first trial, every patient has administered two placebo tablets for one week. Whereas two tablets of the know laxative, Biscodyl 10 mg, were administered, for one week, to every patient in the second trial. And in the third trial, boiled infusion of 200 mg of Senna leaves was administered daily for one week; Two weeks interval was left between every two sequential trials. The results showed that Senna leaves have caused 12.3% decrease in systolic pressure and 8.4%decrease in diastolic pressure, whereas the pulse rate was not statistically significant changed. Also the results showed that the placebo and Bisacodyl tablets did not change these measurements in the mentioned patients