ABSTRACT
Carbapenems are antibiotics of last resort reserved for severe infections with resistant germs, and the abuse of which makes us fear the emergence of resistance to carbapenem. The objective of this survey is to evaluate the relevance of carbapenem prescriptions in the Mohammed VI CHU in Marrakech. This is a prospective evaluation performed on a given day in January 2017. Included were all hospitalization services at the Arrazi Hospital and the Mother Child Hospital of the Marrakech CHU Mohamed VI, including resuscitation services. The investigation concerned all hospitalized patients present in the department on the day of the survey and for whom a carbapenem prescription was made. During the study period, 30 patients were prescribed carbapenem, 63% in intensive care units and 37% in surgery. This carbapenem mainly concerned adults [57%] followed by newborns [33%]. The reason for introducing carbapenem antibiotics was mainly sepsis [46, 5%]. Carbapenems were prescribed as second-line therapy after initial clinical treatment [73, 5%]. The imipenem was the most frequently prescribed carbapenem [83, 5%]. 80% of the infections justifying this prescription were nosocomial. A prescription after microbiological documentation was only found in 9 cases. This evaluation helped to better understand the typology of carbapenem prescriptions in our context