comparison of hypertonic dextrose and corticosteroid on the treatment of first carpometacarpal osteoarthritis

Osteoarthritis of the first Carpometacarpal joint is a common debilitating problem. Because of the important role of thumb in upper limb function, Pain of the disease, joint's instability and deformity, causes functional disorder of the hand. The usual treatments have various and short term consequences. In this study, the injection of Hypertonic dextrose and corticosteroid in the named joint has been compared. This study was a prospective randomized double blind Clinical trial. In the Physical Medicine and Rehabilitation Clinic of 501 Army hospital, Among the new patients having the inclusion criteria in the year 1388-89, 30 hands were randomized to each treatment group. A Questionnaire on the Patients' demographic identity was filled out, then the variables on this study and the two comparisons were registered right at the beginning of the study and after one, two and six months consecutively. In both groups 6 months after the initiation of intervention, symptom severity through the factors of pain on joint pressure and pain on movement, Gripping, Eating and Dressing function and the maximum lateral pinch strength were greatly improved, but most of the factors [including pain on pressure and joint movement, Dressing and Gripping function] in Dextrose group versus Corticosteroid were improved more significantly. [p<0.05] According to the findings of this study, Dextrose injection versus Corticosteroid could have a better long term effects and might have lesser side effects

[Effect of 10% lidocaine spray on postoperative sore throat]

Sore throat is a common complication after surgery. Application of 10% lidocaine spray on cuff of a tracheal tube maybe associated with decreased risk of postoperative sore throat. The purpose of this study was to determine the effect of 10% lidocaine spray on postoperative sore throat. This double-blind study was conducted at Rajaei Hospital in Qazvin during 2008-2009. Two hundred ASA I-III surgical patients [except the neck surgery] aged 9-81 years and without signs of common cold, were randomly divided into two groups. The subject group received aerosolized lidocaine [5 puffs] on cuff of the tracheal tube before tracheal intubation. The patients in control group received normal saline instead. Later, the patients underwent a standardized general anesthesia. These patients were interviewed when leaving the recovery room and re-questioned for the presence of sore throat the following day in the wards. Data were analyzed using the chi-square test and Fisher's exact test. Findings: Sore throat was present in 29% of subject group and 22% of control group while in the recovery room. Sore throat decreased to 16% and 17% on the day after surgery. There was no significant difference in incidence of sore throat between two groups based on duration of surgery and the patient's sex when in the recovery room or wards. It seems that the application of aerosolized lidocaine on cuff of the tracheal tube before tracheal intubation fails to decrease the incidence of postoperative sore throat