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1.
Maroc Medical. 2010; 32 (2): 84-88
in French | IMEMR | ID: emr-133560

ABSTRACT

Involvement of the hip occurs in 15 to 20% of the rheumatoid arthritis. It engages the functional prognosis. Our objective was to specify the frequency of coxitis among our patients, the ground of its which has occurred and its clinical and radiological characteristics. We conducted a cross study including seventy patients with rheumatoid arthritis according to American college of rheumatology criteria. All patients had a clinical exam with measurement of index of evolutivity and of severity from RA, and radiographs of pelvis. We included 57 women and 13 men with rheumatoid arthritis, the mean age was 35,38 +/- 11,21 year, and mean duration of rheumatoid arthritis was of 11,82 +/- 6,9 years. The diagnosis delay was 2 years. Eleven cases of coxites were noted including 7 women and 4 men. The mean duration of the coxitis was 3,66 +/- 4,24 years with a diagnosis delay of 7,25 +/- 7,75 years. Involvement was bilateral in seven cases [63,63%]. The radiological analysis had objectivised a pinching in 11 cases, erosions in seven cases, an acetabuli protrusion in 4 cases and a secondary osteoarthritis in six cases. Only 2 patients had hip joint replacements. In our rheumatoid arthritis the coxitis is common, correlated with disease duration, delay diagnosis and severity of rheumatoid arthritis. It is often bilateral. It can be very invalidating, justifying an early and correct treatment

2.
Maroc Medical. 2010; 32 (3): 206-210
in French | IMEMR | ID: emr-133581

ABSTRACT

Study the frequency of the reactive arthritis, and specify its clinico-biological and therapeutic characteristics with a review of the literature. We conducted a retrospective study including 22 cases of reactive arthritis. All patients had a clinical exam and serology of the germs accused according to clinical data. Urethral prelevement and coprocultures were carried out in the event of sign of orientation. Eighteen men and four women were included, whose mean age was 34 +/- 11, 79 years. The mean duration of reactive arthritis was of 7,95 +/- 5,89 years with a diagnostic delay of 0,79 +/- 1,55 years. Origin of infection was identified in 12 cases [genital in 10 cases and digestive in two cases]. The clinical presentation was as follows: monoarthritis in six cases, oligoarthritis in 11 cases, polyarthritis in four cases. The heel pain was present in six cases, and the ocular manifestation in form of iritis was noted in four cases. Serology of Chlamydia was positive in 16 cases. Genital taking had isolated a Chlamydia and a mycoplasma in two cases. The corproculture had isolated a shigella in two cases. The treatment comprised anti-inflammatory drugs in 22 cases, antibiotics in 18 cases and intra-articular steroids in 10 cases. Evolution to ankylosing spondylitis was notes in 12 cases [10 men and 2 women]. Reactive arthritis with Chlamydia seems more frequent at the men. The evolution is often towards to ankylosing spondylitis. A prospective study on a large scale could be able to confirm these data

3.
Revue Maghrebine d'Endocrinologie-Diabete et de Reproduction [La]. 2007; 12 (4): 234-241
in English, French | IMEMR | ID: emr-94247

ABSTRACT

This study is presented to raise the awareness concerning the problems of the quality of princeps drugs used in developing countries. Its goal is to show that a drug is the result of a complex balance between a number of parameters and that, for the same active principle, the therapeutic effectiveness is conditioned by the pharmacotechnic characteristics, by the formulation in its galenic form and by manufacturing conditions. The comparison of the in vitro release of metformine from princeps products originating from different countries reveals pharmacotechnic differences: a delayed dissolution suggests a risk of reduction in effectiveness and an early dissolution a risk of overdose. Thus, the dissolution test applied to generic drugs could be of interest in the comparison between different princeps of a same active principle


Subject(s)
Hypoglycemic Agents/pharmacokinetics
4.
Maroc Medical. 1999; 21 (3): 192-194
in French | IMEMR | ID: emr-51724

ABSTRACT

The severe acute asthma is a frequent complication of the asthma which threatens the life of patients. Therapeutic objective in the severe acute asthma is to play rapidly on the bronchial obstruction components. The adrenaline, by its alpha actions which are theoretically benefic, allowing the reduction of the bronchial oedema and by its B-2 agonists which has a strong bronchodilator action, is indicated in the treatment of the severe acute asthma after failure of the B-2 agonists. The objective of this article is the study of the actions of the adrenaline and its use in the treatment of the severe acute asthma


Subject(s)
Humans , Epinephrine , Acute Disease , Epinephrine/administration & dosage , Epinephrine/pharmacology
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