Alpha heavy chains disease: an intermediate stage

The authors report a case of alpha heavy chains disease associated with a lambliasis affecting a forty-year-old Moroccan women. Histologically, the stage of this case has not been described yet. It is intermediate between the stage A and B: there is a transparietal and plasmocytic infiltration of the small bowel as well as a ganglionic and periganglionic mesenteric infiltration and without any immunoblastic participation. This particularity warrents the tetracycline and cyclophosphamid association. This study is completed with a review of literature dealing with the alpha heavy chains disease

[Persistent cholestatic hepatitis. Diagnostic and therapeutic interest]

The authors report 9 cases of persistent cholestatic hepatitis treated by corticoids. After having defined the selecting criterions of the different observations they note that the period of disappearing of the jaundice by cortico-therapy doesn't go beyond 30 days except for one patient for whom the jaundice was of an excessive long continuance. Biologically, the authors insist on the lack of normalisation of alkaline phosphatase while the other hepatic investigations become nearly normal