Subject(s)
Humans , Male , Female , Depressive Disorder, Major , Psychiatric Department, Hospital , Hospitals, UniversityABSTRACT
Authors report the results of a controlled randomized study about 64 patients followed in the psychiatric external consultation of the university hospital center of Monastir. All the patients are using antianxiety drugs for a long time and correcpond to the DSM III R criteria of psycho-active substance dependence. The main psychiatric indications are affective disorders, domatoform disorders and anxiety disorders. The patients have been divided into 4 groups: the first and the second group have respectively been submitted to an immediate, entire substitution [G1], and progressive substitution [G2], of the tranquilliser with a placebo. The third group [G3] have undergone a progressive decrease without placebo, and the fourth group [G4] is a proof group. A quantitative assessment have been performed with Hamilton's anxiety scale at JO, J 15, J30. Level's anxiety remained at an average intensity for all the groups at J 15 and J 30. The analysis of the reactions at the arrest or at the progressive decrease of the treatment, allowed to observed 15 cases of bounce anxiety among G1, G2, G3 and 4 cases in the proof group. A preventive management is recommended to reduce the risk of chronic recourse to a tranquilliser treatment