[Prevalence of sexual mutation rate abnormalities in patients with beta thalassemia in Iran]

Background: thalassemia is accounted as the most common hereditary anemia through our region. Due to abnormality in synthesis of globin chains in red blood cell resulted from this disease, these globules have not natural life and then will die immediately. Appropriate therapy for this disease includes a regular monthly blood injection. However, in the approach patients will inevitably confront with side effects particularly iron overloads and iron sediment along tissue of body critical organs including heart, ductless glands and liver. Examining more research examples, by the study it attempted to determine more precisely plenty of adenoidal abnormality between the Iranian thalassemia patients for pre diagnosis and offering necessary medical measures

Materials and Methods: this was a descriptive research and included all the patients suffering from thalassemia major referring to medical centers linked with the Iranian blood transition institute. Census applied for sampling from all the patients. Initially, reports of adenoidal experiments as well as other associate parameters provided from medical folders

Results: from 437 understudy thalassemia patients, sexual mutation rate [SMR] was investigated along various age groups. There was no difference in those patients who, suffered from intermediate thalassemia and there was no relation between various age groups in the case of SMR classification [P=0/00]. Average of ferritin had no statistic difference among al 5 groups [P=0/6]

Conclusion: comparison of results between present research and similar studies conducted through Iran and those performed in abroad on growth abnormalities and puberty in thalassemia patients show that subject patients of this study statistically suffer from fewer difficulties than in case of patients in other studies

[Neutropenia in child: Report of 3 cases]

Background: neutropenia is a condition of absolute neutrophil count of less than1500/ml. Neutropenia May occur as either acquired or congenital disorder

Case: there neutropenic patients who are reported here have suffered from skin Infections, gengivostomatitis, and lymphadenitits. They have been well between these neutronpenic periods. One of the patients had developed neutropenia after a 3year period of zaditen administration. Another one had cyclic neutropenia and the last patient has been neutropenic from the infancy