Effect of Clupeonella grimmi [anchovy/kilka] fish oil on dysmenorrhoea

To examine whether dietary supplementation with omega-3 fatty acids from Clupeonella grimmi can relieve symptoms of dysmenorrhoea, we carried out a cross-over clinical trial on 36 girls aged 18-22 years. They were randomly allocated into 2 groups of 18. Group A received 15 mL fish oil daily [550 mg eicosapentaenoic acid; 205 mg decosahexaenoic acid] while Group B received placebo. After 3 months, the treatment regimens were swapped. The treatment groups reported a significant difference after 3 months of supplementation with fish oil [visual analogue scale score 20.9 compared with 61.8 for the placebo [P = 0.001]. There was also a marked reduction in low back pain and abdominal pain [P < 0.05], and participants needed significantly fewer rescue doses of ibuprofen while using fish oil

comparison on histopathological effects of myrtle extract and silver sulfadiazine 1% on healing of second degree burn wound in rats

Myrtle [Myrtus Communis] is an indigenous plant of northern parts of Iran and has been traditionally used for its healing effect on burn wounds. To compare the histopathological effect of Myrtle extract and 1% silver sulfadiazine on healing of second degree burn wound in rats. This was an experimental study performed on 100 adult male rats. The rats were divided into 4 groups [25 in each group]. Following nesdonal anaesthesia, a second degree burn wound of 4 cm2 was made on back of each rat. Methanolic extract of Myrtle; ointment base; 1% silver sulfadiazine and normal saline [control group] were used as treatment protocols for burn wounds. Revascularization, number of neutrophils and fibroblasts were parameters studied histopathologically. Data were analyzed using Chi-square, Kruskal-Wallis, One way ANOVA and Tukey's HSD tests. Histopathological study was indicative of an increase of 9.87 +/- 1.48 in revascularization [p<0.001] in Myrtle extract group which was greater than those in other. There was also a higher number of fibroblasts [23.62 +/- 2.2] [p<0.001] in this group. Silver sulfadiazine [1%] was only showed to have increased the number of neutrophils [p<0.001] in epidermis of injured areas of rats. Extract of Myrtus Communis was found to have more healing potential on second-degree burn wound. Faster healing process, less complications and easy availability of Myrtle are among the reasons suggesting more clinical trails using this preparation..