Combined liver and kidney transplant for a pa patient with primary hyperoxaluria: 11 years Follow-up

We report a 30 year-old male who developed end - stage renal disease at the age of 12 years due to primary hyperoxaluria. After six months of heamodialysis he received a cadaver kidney transplant. Five years later the allograft failed because of heavy oxalate deposition. After three months of heamodialysis he received combined liver and kidney transplant with the immunosuppression of Tacrolimus and prednisone. Now after 11 years of follow up he has normal liver functions, stable renal function with serum creatinine around 200 micro mol/L and normal daily urine oxalate excretion. This case illustrates the long-term success of combined liver-kidney transplantation for treatment of primary hyperoxaluria with renal failure