ABSTRACT
Honey has been generally used in traditional medicine for healing different kind of wounds. In this research complex, the clinical and histopathological effects of West Azarbayjan non-boiled honey in healing process of surgical wounds [cuts] were evaluated. This study was performed to evaluate the effect of honey on healing time and duration of wound closing in dog. 30 dogs, each weight was almost 25kg, were divided into 2 clinical [n=10] and histopathological [n=20] groups. In each group, after surgical preparation and anesthesia surgical wounds were produced by a similar pattern and size [rectangle; 25×50 mm[2]] in the thoracolumbar region. Wounds on the left side arbitrary taken as treatment group and on the right side as control group. Postoperative treatment in the honey group was included daily wound irrigation with normal saline and then topical application of 20g honey. In the control group only irrigation with normal saline was performed. Clinical and histopathological parameters were evaluated in each group 7, 14, 21 and 28 days after operation. Honey caused in acceleration an healing and surgical wound closure and in decreasing the level of infection and secretion in the experiment group in compare to control group which was more significant at days 14 and 28 [p<0.05]. Decreasing the area of wound during experiment in honey treated group was 11.1% more than control group. From histopathological aspect, especially from the second week on, less neutrophilic chemotaxis was found in treatment group than in the control group and in treatment group the compact connective tissue was developed more rapidly. West Azarbayjan non-boiled honey is potentially effective in surgical wound healing
Subject(s)
Animals , Wound Healing , DogsABSTRACT
The prevalence of the latent form of sheep abomasal phytobezoariasis and the effect of husbandry management on this condition were determined in a survey in and industrial abattoir in Urmia from June 2005 to July 2006. The effect of different age groups and seasons on the prevalence of sheep abomasal phytobezoariasis was also determined. Furthermore, the histological changes in the affected abomasal tissue were also verified. The breeds and ages of the sheep were identified prior to slaughter. In the postmortem, the abomasum was examined for foreign bodies, including bezoars. Tissue specimens were taken from the abomasal body in the affected cases. The annual prevalence of sheep abomasal phytobezoariasis was 1.95%. The prevalence was highest in the Makuei breed and the lowest in Ghezel sheep. The prevalence was higher in winter compared to other seasons. The number of phytobezoars per abomasums ranged from one to four. The histopathological changes in the affected cases included leukocytic infiltration in the mucosal layer, edema, glandular hyperplasia and cystic spaces
Subject(s)
Animals , Breeding , Seasons , Age Factors , Prevalence , Bezoars/epidemiologyABSTRACT
The objective of this study was to determine the effectiveness of topical administration of honey in prevention of or reduction in post-surgical peritoneal adhesions in dog. The study was conducted on 18 adult female mixed-breed dogs with a mean +/- SD weight of 20 +/- 4.25 kg. A standardized surgical trauma [serosal trauma model] was made in the dogs' descending colon to induce adhesion formation. The control group [n = 9] received saline treatment. In the experiment group [n = 9], the lesions were covered with honey. Three weeks after laparotomy, the dogs were sacrificed and the adhesions were graded according to the Evans's scoring system. Overall, 67% [n = 6] of the control and 22% [n = 2] of the experiment animals presented with moderate [grade-2] and severe [grade-3] adhesions. In the control group, there were 3 [33%] dogs with grade-0 or grade-1 adhesions, while in the experiment group there were 7 [78%] dogs with the same grades of adhesions. The difference between the two groups was significant [P<0.05]. It was concluded that honey is a useful covering for damaged peritoneal surfaces and has high effectiveness in reducing post-operative adhesions