Antihyperglycemic effect and nutritive value of opuntia dillenii [Ker-Gawl] haw. fruits cultivated in Egypt

The antihyperglycemic effect of the fruit juice of opuntia dillenii [Ker-Gawl] How [cactaceae] as well as that of the mucilage and pectin, was studied in alloxan-induced diabetic rats through actute and long-term [8 weeks] experiments The chemistry of the isolated mucilage and pectin Was also demonstrated by GC-MS. Chemical characterization, as well as investigation of the nutritive profile of the edible portion of the fruits were also carried out

Anti-hyperlipidemic effect and lipoidal constituents of grewia asiatica L. leaves

The aqueous ethanol extract, as well as, successive extracts of the dried powdered leaves of the plant were investigated for their anti-hyperlipidemic activity in induced-hyperlipidemic rats. The obtained data were statistically analyzed using Student's 't' test. Significant reduction in triglyceride and cholesterol levels were observed especially with the petroleum ether extract. Bioassay-guided fractionations have led to the fractionation of the petroleum ether extract by colunm chromatography. The hydrocarbon fraction was isolated and its components were identified by GC/MS analysis which revealed the identification of 50 compounds. Six triterpenes, two sterols, one diterpene and four fatty alcohol's were isolated and purified. They were identified by determination of their spectral data as: [1] beta-amyrin [2] alpha-amyrin [3] alpha-amyrone [4] friedelin [5] glutin-5-en-3-ol [6] lanost-9 [11]-en-12-one [7] stigmast-7-en-3-ol [8] beta- sitosterol [9] phytol [10] docosanol [11] hexacosanol [12] heptacosanol and [13] nonacosanol. The fatty acids fraction was prepared, methylated and its components were identified by GC/MS analysis which revealed the identification of 16 compounds. It is worth to mention that the antihyperlipidemic activity test, as well as, the isolation of the identified compounds from G. asiatica leaves are carried out for the first time in the present study