Clinical and biochemical characteristics of polycystic ovary syndrome in Benghazi- Libya; a retrospective study

Polycystic ovary syndrome [PCOS] is a common endocrine condition affecting women of reproductive age and characterized by chronic anovulation, hyperandrogenism, and polycystic ovaries. There are no published data on this syndrome in Libyan patients. To assess the frequency of clinical and biochemical features of PCOS in our patient population, and to compare this with data collected in other parts of the world. A retrospective analysis of patient records at the endocrine clinic in Benghazi was undertaken. Patient inclusion was according to Rotterdam ESHRE/ASRM criteria. Clinical features, associated diseases, family history, hormone levels, and ultrasonography results were analyzed. The mean age of the 318 PCOS patients at presentation was 25.8 years [range 15-44 years], and the majority [67%] were 20-29 years old at presentation. Of all patients, 57% were obese [BMI >/= 30], 93% had oligo- / amenorrhea, 91% were hirsute, and 74% had ultrasound features of polycystic ovaries. Diabetes mellitus was diagnosed in 9% of all PCOS patients and hypertension in 4%. Total serum testosterone was elevated in 26% of the patients, and serum prolactin was elevated in 31%. Thyroid disease was noted among 5.3% of the patients, and a history of diabetes or hypertension among first-degree relatives was seen in [16%] and [8%] of the patients respectively. Chronic anovulation and hirsutism are the dominant features of PCOS in our patient population. More than half were obese, and the prevalence of diabetes, hypertension and thyroid disease in our patients seemed to be underestimated in comparison to other parts of the world

Incidence and pattern of hyperprolactinemia in Benghazi, Libya

A retrospective study for a period of 7 years in 7th april hospital, Benghazi, libya, identified 37 cases of hyperprolactinaemia. The interval between the start of the symptoms and diagnosis ranges from 2 months to 15 years. The causes of hyperprolactinaemia include prolactinoma in 5,druginduced in 5, ovarian cyst in 2, hypothyroidism in 2, chronic renal failure in one and remaining were idiopathic in 22 patients. The patients presented with galactorrhoea [62%], amenorrhoea [51%], infertility [37%], headache [32%], and hirsutism. Five patients with pituitary tumour were treated with surgery and bromocriptine. Other patients were given bromocriptine. They all improved