Seizure as a presenting manifestation of idiopathic hypoparathyroidism

A 31-year-old male presented with generalized new-onset tonic-clonic seizure related to severe hypocalcaemia [serum calcium 1.2 mmol/l] caused by idiopathic hypoparathyroidism [parathyroid hormone concentration 6pg; normal 15-65pg]. Computerized tomographic scan showed bilateral, symmetrical, intracranial calcifications involving the basal ganglia and the cerebellum. There are few reports in clinical literature describing new-onset seizure caused by primary hypoparathyroidism in adulthood and hypoparathyroidism needs to be considered in the differential diagnosis of adult-onset seizure