ABSTRACT
A recognised and reliable methods were used to measure serum glucose level in fifty seven patients with different histologic types of primary lung cancer. Statistical analysis of the data revealed a significant increase in the level of serum glucose in all histologic types [P< 0.001, P< 0.02, P< 0.01 and P< 0.001]. The change in this parameter pre and post operatively might be of value in staging and follow up of patients with bronchogenic carcinoma.
Subject(s)
Humans , Female , Male , Blood Glucose , Carcinoma, Squamous Cell , Carcinoma, Small Cell , Carcinoid Tumor , AdenocarcinomaABSTRACT
A recognized and reliable methods were used to measure serum total protein and its electrophoretic patterns in fifty seven patients within different histologic types of primary lung cancer. Statistical analysis of the data revealed a significant decrease in the level of serum total protein and albumin [P<0.001 and <0.001 respectively]. With the respect to normal control groups. While serum globulin fractions showed significant increase than the control group in most histologic types. All these biochemical abnormalities were returned to normal state after surgical operation. Most of these parameters measured in this study might be of value in differentiation between different histologic bronchogenic carcinoma
Subject(s)
Humans , Male , Female , Blood Proteins , Blood Protein Electrophoresis , Carcinoma, Squamous Cell , Carcinoma, Small Cell , Carcinoid Tumor , Carcinoma, Large Cell , AdenocarcinomaABSTRACT
A recognized and reliable methods were used to measure serum calcium, Magnesium, inorganic phosphorus, parathyroid and calcitonin hormones level in forty one patients with different types of bone tumors. Statistical analysis of the data revealed a significant decrease in the serum levels of calcium, magnesium and inorganic phosphorus [p<0.01; p< 0.001 and p<0.0 respectively]. Serum parathyroid hormone level was significantly increased [p<0.001], while calcitonin level did not show any significant change. The biochemical changes were only found in malignant bone tumor, since no changes were detected in benign type. All these biochemical abnormalities return to control value after surgical operation and during anticancer therapy in patients with primary malignant bone tumors. While in patients with secondary bone tumors the above biochemical changes were persisted inspite of treatment. These results show that the measurement of the serum levels of the above mentioned biochemical parameters are of a great value for the diagnosis and prognosis of primary bone tumors