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1.
Bulletin of High Institute of Public Health. 2007; 37 (4): 888-903
in English | IMEMR | ID: emr-172472

ABSTRACT

In the current study on lactation in rats' dates [D] ratio in diet was examined in supporting this physiological case. Dates were used both at 25 or 50% with another food sources such as dimmed milk [SM] at 10 or 30% plus a source for CHO such as sweet potatoes [SP] at a variable ratio of 10, 25, or 35%. A special herbal mixture of extract as additives [AD] was added to all groups except the NC. The NC control composition was 46% both SM and corn starch [S], wherein the ratio proteins in diet, almost 17.5%, was corrected using 10 or 20% of a plant-rich protein antioxidant semimodified food [AC]. Date has been found to be preferable up to 25% in a special combination as Iactating diet. The food component of the best diet under the condition of this experiment, i.e., the et met the most healthy both mothers and infants, were the skimmed milk [SM] of 10% plus sweet potatoes [SP] at a high ratio of 25%. It seems that little higher ratio of proteins, i.e., 18%, most of which are plants with plenty amount of vegetable CHO and less than 10% fat in oily form with an adequate amount of minerals and vitamins, particularly found in D and SP, are important food toleration for those rats. This is formally seen in pregnancy. Fortunately, the diet of choice according to the above mentioned role gave also the optimal 8W measurement. However, rapid weight loss through diet or medication should not be attempted during lactation. Under the light of blood cell counts, blood analysis and both liver and kidney histopathology, the special extract used seemed to be important as source for some minor elements. The conjugation of those micronutreints and the macronutreints provided by the food system mentioned above has strongly supported that sort physiological nutritional requirements. Lactation is a special physiological case with a specific metabolic hormonal balance. This is an adapted hormonal shift [HS] follows this particular physiological status. It is such a hormonal program that strongly connected to feeding category. The present data show an alternative food combination that support mother health based on biological evaluation used, i.e., liver function and histology was group 4 of 25 D, 10 AC, 30 SM, and 25 SP. More investigation is needed to observe the role of the food additives used in the presence of main nutrients on this profounded kind of hormonal status


Subject(s)
Female , Animals, Laboratory , Rats , Animal Experimentation , Milk , Food, Formulated , Dietary Supplements , Liver/pathology , Histology
2.
Bulletin of High Institute of Public Health. 2007; 37 (4): 904-919
in English | IMEMR | ID: emr-172473

ABSTRACT

Food is of great role in human health. The best goal in this concept is variety in the diet and moderation. This hypotheses has been observed on bases of nutritional biochemistry. A single good, i.e., phasoluse bean, was used at rates of 30, 50, and 100% replacements of the basal diet for aged rats. It was clear that the higher rate of morbidity and mortality due to this sort of malnutrition, or semistarvation, has been associated with, some biological changes. Although beans is rich in containing proteins, the partial replacement of this plant food origin at 30% has shown to be a good help in keeping an optimal body weight [BW] of those aged animals, but any more degree of replacement has seen to be vital in affecting the animal health, hence 50% or over might resulted in animal death. It seemed that 25% may be useful in mentaining BW, meanwhile, a further rate of this plant origin replacement up to a specific level should be an effective way in treating obesity if used in a proper dietary system. In more details, organ morphologies and histopathologic examination of some of which as spleen, brain, and liver are greatly affected by imbalanced diets. In another word, the metabolic differences rolled up by this sort of feeding negatively affected liver and brain expectancy or longevity. A number o tissues upnormality, such as liver tissues dilatation and congestion of hepatoportal vessels, hepatocytes karyomegIy nuclei, congestion of central vein, and granular degeneration of hepatocytes with both most higher rates of replacement groups. Moreover, there were focal gliosis, pyknosis of neurons, brain edema, and hemorrhage in cerebrum and cerebellum in brain of the same groups. It is obvious that all these organ dysfunction are frequently occurred as a response to these and similar kind of malnutrition, other than energy one, that has been existed for a long enough time. This weak homeostatic system has been shown as less control on the metabolic constants such as blood glucose [G], triglycerides [TG] and total cholesterol [TC]. All those are most likely correlated with the organs subclinical defects mentioned before. It seems that this biological control that actually supported in the presence of balanced d]et can be a biological upregulatory mechanisms, and the death eventually occurs due to a protein catabolic pathway due to a protein, the quality but not only quantity, malnutrition. It is an emergence metabolic system [EMS] that runs for longer time caused by a strengthen need for some micronutrints as well as high rate of nitrogenous metabolite accumulation. This protein turn over in such high rates beyond the biological capacity of both intracellular and extracellular compartments negatively affect the whole biological system including cells, tissues, organs, and eventually the blood chemistry as well. Refeeding with a proper system of animal high quality protein and some micronutrints might be vital


Subject(s)
Animals, Laboratory , Rats , Nutritional Status , Malnutrition , Body Weight , Organ Size , Liver/pathology , Brain/pathology , Histology
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