ABSTRACT
Background and Objective: acne rosacea is a chronic skin disease with unknown etiology. Some reports have suggested an increased prevalence of helicobacter [H] pylori infection in patients with acne rosacea but it is controversial. This study was designed to compare the prevalence of H pylori between the acne rosacea patients and the healthy control group
Materials and Methods: this case-control study was performed on 30 patients with acne rosacea and 60 healthy individuals as a control group. 5 mL blood was taken from each person and anti-H pylori IgG was measured by enzyme-linked immunosorbent assay
Results: mean age was 45.8+/-14.05 years in acne rosacea patients and 41.4+/-12.3 years in control group. Seventeen [56.7%] of patients and fifty two [86.2%] of controls were infected by H pylori [P=0.002], but mean serum anti-H pylori IgG level was significantly higher in acne rosacea patients comparing to healthy control group [139.49+/-174.15 g/mL vs 38.87+/-23.50, P=0.005]
Conclusion: despite increased mean serum anti-H pylori IgG levels in acne rosacea patients, H pylori was more prevalent in healthy control group, in this study