Effects of circuit resistance training intensity on the plasma ghrelin to obestatin ratios in healthy young women

Ghrelin and obestatin are orexigenic and anorexigenic peptides, respectively. It appears that an accurate balance between theses peptides is important for regulating energy homeostasis and body weight. The aim of this study was to identify the possible mechanisms by which circuit resistance training influences energy homeostasis and weight control. Twenty-seven female students with the mean age of 22 +/- 1.54 years and mean body mass index [BMI] of 20.76 +/- 1.86 kg/m2 were selected and randomly divided into experimental and control groups. Subjects performed circuit resistance training with 40% and 80% of 1 repetition maximum [1RM] for 4 weeks. Total plasma ghrelin, obestatin, and glucose levels and the ghrelin to obestatin ratio were measured for all subjects before and after training. One-way ANOVA tests showed that, the plasma ghrelin to obestatin ratio increased significantly in the 80% 1RM group [P < 0.05]. Furthermore, a significant reduction of the plasma obestatin level was found in this group [P < 0.05]. It appears that an energy deficit caused by circuit resistance training in 80% of the 1RM group resulted in the ghrelin precursor being increasingly used for ghrelin production. Thus, obestatin secretion decreased and the ghrelin to obestatin ratio increased in order to stimulate food intake and lost energy resource consumption to eventually restore the energy balance in the body

effect of Ramadan fasting and weight-lifting training on plasma volume, glucose and lipids profile of male weight-lifters

The purpose of the present study was to evaluate the effect of Ramadan fasting and weight-lifting training on plasma volume, glucose, and lipids profile of male weight-lifter. Forty male weight-lifters were recruited and divided into 4 groups [n=10 each] and as the following groups: control [C], fasting [F], training [T] and fasting-training [F-T]. The T and F-T groups performed weight-lifting technique trainings and hypertrophy body building [3 sessions/week, 90 min/session]. All subjects were asked to complete a medical examination as well as a medical questionnaire to ensure that they were not taking any medication, were free of cardiac, respiratory, renal, and metabolic diseases, and were not using steroids. Blood samples were taken at 24 hr before and 24 hr after one month of fasting and weight-lifting exercise. The plasma volume, fasting blood sugar [FBS], lipid profiles, and lipoproteins were analyzed in blood samples. Body weight and plasma volume showed significant [P< 0.05] decrease and increase in the F group [P< 0.05] respectively. Also, a significant reduction was observed in F-T group body weight [P< 0.01]. A significant increase was found in FBS level of F group [P< 0.05]. The lipid profiles and lipoproteins didn't change significantly in C, F, T and the F-T groups. The effect of Ramadan fasting on body weight and plasma volumes may be closely related to the nutritional diet or biochemical response to fasting