ABSTRACT
Objectives: The aim of this study is to describe the clinical and electrophysiological and therapeutic outcome of those patients with Geriatric guillain-Barre' syndrome
Patients and Methods: Guillain-Barre' syndrome in patients older than 60 years of age were collected and HUGES disability score was used to quantify neurological deficit and outcome after therapeutic trials
Results: 18 patients were included at this study with a mean age of 64, 8 years. 80% of them was found to have sensory - motor deficit. Evidence of demylination was found in 8 subjects and axonal deficit was found in another 6 subjects there were only one with Miller-Fisher syndrome and 3 unclassfied. Plasmapharesis was carried out to 12 patients and [IVIg] in 2 patients. No significant difference between the two groups as regarding disability score before treatment .no significant difference in outcome in both groups after treatment
Conclusion: Axonal GBS are more frequent in elderly and this may have a prognostic clue. plasmapharesis and IVIg treatments have no significant difference in outcome but with more complications at plasmaphresis than IVIg