Impact of Sildenafil on Smooth Muscle and Blood Vessels by Using Light and Electron Microscopy.

The present study aimed to examine the histological changes in the smooth muscles of corpus cavernosum and veins of rats as an eventual outcome of the ceaseless use of Sildenafil citrate. The comparison of the histological aftereffects of the veins among the control and experimental groups revealed extended thickness of tunica intima and media, as exhibited by a picture analyzer. The findings indicated that the steady usage of Sildenafil reduced smooth muscles and enabled the growth of collagen fibers in corpus cavernosum of penis and mass of veins.

Effect of psychotherapy on the quality of life in cancer larynx patients

To study the effect of psychotherapy the quality of life of cancer larynx patients treated by total laryngectomy. Prospective cohort study. 18 patients were divided into two groups, group A [10 patients] received psychotherapy pre and then post laryngectomy, while group B [8 patients] didn't receive any form of psychotherapy. Both groups were compared as regards psychological well being and quality of life using depression scale, anxiety scale, hopelessness scale, suicidal ideations scale QQL questionnaires. Psychotherapy has a positive effect on quality of life in cancer larynx patients

protective role of flavonoids on the cardiac muscle during the development of myocardial infarction

In this study, three common natural flavonoids [sour orange, sweet orange and salvia] known to have positive cardiotonic effect were chosen and their ability to inhibit apoptotic death of cardiac muscles and the extent that they could protect them during evolving myocardial infarction were tested. The three flavonoids influenced the apoptotic cell death. The elevated creatine kinase isoenzymes [CK MB] and lactate dehydrogenase [LDH] levels were significantly decreased. Also, the decrease in QRS volts and the increase in the heart rate, which were observed in cardiac infarction, were significantly improved. Thus, it was concluded that the three flavonoids, with variable degrees, influenced the apoptotic cell death in the cardiac muscle and protected the heart during evolving MI by decreasing the degree of tissue necrosis. Also, they can improve the performance of the heart and decrease the incidence of ventricular fibrillation