Relation between antioxidants and pollution on experimental animals

The aim of the present work is to study the protective effect of some antioxidants and trace elements against the hazardous effects of carbon tetrachloride [CCI[4]] on hamsters for the possibility of further application on humans. One hundred twenty hamsters weighing 104-128g were divided into 13 groups as follows: 1-Negative Control group fed standard diet, 2-positive control group given carbon tetrachloride CCI[4] only, 3-CC1[4] + zinc, 4 - CCI[4] + beta-carotene,9- CCI[4] + alpha- tocopherol, 6- CCI[4] + selenium. 7- CCI[4] + vitamin C,8- CCI[4] + zinc + beta - carotene, 9- CCI[4] + zinc + vitamin C, 10- CCI[4] + zinc + alpha-tocopheral, 11- CCI[4] + selenium + beta-carotene, 12- CCI[4] + selenium + vitamin C and 13- CCI[4] + selenium + alpha-tocopheral. Carbon tetrachloride [CCI[4] has a direct toxic effect on liver and kidney. Depending on biochemical results, the more antioxidants of liver protection against [CCI[4] toxicity are a tocopherol, followed by selenium, selenium + beta - carotene, vitamin C, zinc + beta - carotene and selenium + alpha tocopherol. The more antioxidant for kidney protection against CCI[4] toxicity is beta -carotene followed by selenium, zinc + beta - carotene, zinc + alpha tocopherol, and zinc + vitamin C. Trace elements should not be given individually especially zinc or selenium as deleterious effects, in spite of its protective effect

Effect of food intake on lipid pattern of young adults in Beheira governorate

This study was conducted in Beheira governorate during 1999. Three districts were chosen [Rashied Delengat and Damanhour] on the assumption that their populations differ in their food habits. The study included 197 males and 169 females from both rural and urban areas in each district. The mean age of the males was 21.3 years and for females was 20.2 years. Fasting blood sample for plasma was collected from each subject to study the effect of food consumption on plasma lipid pattern as a risk factor for atherosclerosis. Total cholesterol, HDL-C, IDI-C and triglycerides were determined for each subject and their food intake was recorded. The results indicated that prevalence rates for hypercholesterolemia were 12.9%, 12.7% and 4.2% in males and 18%, 17.5% and 15.6% in females in rashied, damanhour and delegate, respectively. On the other hand, hypertriglyceridemia was recorded in 16%, 27% and 19.4% of males in Rashid, Damanhur and Delengat, respectively compared with 23% 24.6% and 31.4% in females, respectively. The study recommended that nutrition education is needed for touth and young adults and the encourarge practice of sports in the both urban and rural areas. Further studies should be conducted in other governorates to identify the prevalence of risk factors for atherosclerosis among youth