ABSTRACT
Multiple medication use is especially common in those with diabetes aged due to multiple illnesses, certain chronic diseases and disabling of the growing demand for care, treatment advances, but also some over-prescription. To assess the achievement of treatment goals in a population of older diabetics, to analyze drug consumption and to derive a practical driving prevention. This descriptive retrospective study was interested in 600 cases of diabetic patients older than 60 years, recruited from the diabetes followed at the National Institute of Nutrition and Health Unit in Tunis Sidi Hassine involving three local clinics to during the years 2009-2010. The average age of the study population was 70 +/- 0.5 years with extremes from 65 to 92 years. In our study, 91% of patients between 2 and 5 chronic diseases and the majority of subjects suffering from disabilities. The number of drugs prescribed in our subjects [all dosage forms combined] varies between 1 and 4,with a peak of interest to patients treated with 2-4 drugs, encountered in 91% of cases. The similarity of shapes and colors of certain drugs often confusing. Multiple medication use is common in older diabetic subjects. Hence the need for good coordination between prescribers to prevent abuse and ensure the correct therapeutic education of patients and their families
Subject(s)
Humans , Male , Female , Aged , Retrospective Studies , Patient Medication KnowledgeABSTRACT
At the obese ones, there is an imbalance between the free defenses antioxydants and radicals from where the installation of an oxydative stress, responsible for the development of non-insulin dependent diabetes. Our objectives was to evaluate the levels of vitamins A, E and of leptin, to search the link witch could exist between vitamins and leptin. We proportioned the rates in vitamins A, E and in leptine at 30 obese subjects diabetic of type 2 including 12 men and 18 women of average age [50,93 +/- 6,13] years not carrying pathologies other than the diabetes and obesity compared to 30 witnesses who theirs are paired according to the age and the sex. Our results chows that levels of antioxidants did not differ between the two groups but we find a non significant decrease in vitamin El [TC +TG] ratio [1,86 +/- 0,38 VS 2,11 +/- 0,74 ; p=0,08] and significant increase of vitamin A level in women obese with non-insulin-diabetes mellitus compared with control group of women [0,69 +/- 0,16 V.S 0,55 +/- 0,15 ; p=0,01]. Moreover a negative and significative correlation between vitamin E and leptin [r=0,452 p=0,01], and a negative and no significative correlation between vitamin A and leptin [2=-0,221 ; p>0,05] were observed. the rate of vitamin A, is different for each sex with share. The vitamin E could have a negative control on the secretion of the leptin