ABSTRACT
Introduction: The purpose of this study is to evaluate effect of moderate endurance training activity on cellular antiaging process by modulation of telomeraze enzyme content in cardiac tissue and penipheral blood eylymphocytes in male rats
Methods: Samples were rats provided by Pastear Institate of Iran. They were randomly assigned into two groups leacth composed of 8 rats
Results: 2 weeks ware allocated for adaptation to environment and changes of biological rhythm [1[st] week], and familiarity with treadmill [2[nd] week]. major protocal began after that, which includes a session of moderate daily exercise for fine days per week. Exercise continued for 16 weeks whilk the control group were sedentary. During the 1[st] eighth weeks speed of ranning on treadmill increased from 15m/min to 25m/min and reine from 15 minutes to 25 minutes progressirely, but in tensity was unchanged during the 2[nd] eighth weeks period. One day after and to the protocol, Samples were collected in fasting situation. the results showed that moderate endurance training Downloaded from jmciri.ir at 16:40 +0430 on Tuesday July 10[th] 2018 have a statistically significant effect on increasing telomerase enzyme content in cardiac tisswe [P=0/004], and lymphoeytes [p=0/004]
Conclusion: In Summany, resalts sugyested that moderate, regulaer physical activity [60-65% vozmax] have an induction effect in telomerase content and length stabilily, which in turn lead to cellular viability improvement and genomic stabilily that ploy an anti-aging role