ABSTRACT
Background: The mastery and supervision of traditional medicine in our country, particularly Senegal, would be of capital importance for the population. We were interested in the physiological effects of Voacanga africana (VOC) extracts in wound healing and topical inflammation. Aims and Objectives: This work was to evaluate the effects on inflammation and tissue repair of an hydroethanolic extract of V. africana. Materials and Methods: Wounds were created from a rat burn model and wound healing was evaluated (Kamoshida method) topical inflammation in a murine model of croton oil-induced inflammatory edema. For each experiment, batches of rats or of a mouse were formed, and every batch included five animals. Results: VOC’s 30% root bark ointment showed complete healing by day 16 for the burn test. As for inflammation, the 10% ointment inhibits 80% of the inflammatory edema in the same manner as indomethacin, used as the standard anti-inflammatory drug. Conclusion: VOC could have dose-dependent effects on inflammation and burn healing.
ABSTRACT
La presente etude a porte sur la frequence et l'etiologie des teignes en milieu scolaire de Nouakchott. Sur les 1.233 eleves examines; 179 ont presente des lesions cliniques caracteristiques; soit 14;5 pour cent; parmi lesquels 147 sont positifs sur le plan biologique (culture et/ou examen direct) soit une correlation de 93;8 pour cent. Il n'y a pas de difference significative entre les deux sexes; cependant; il y a une difference entre les groupes d'age ou le groupe de 7 a 10 ans est le plus touche; et la prevalence diminue avec l'augmentation de l'age. Il y a egalement une difference significative entre les differents quartiers; avec plus de 22 pour cent dans les quartiers de bidonvilles. La repartition etiologique montre une predominance du trichophyton violaceum (67;34 pour cent) suivi de trichophyton soudanensis (27;86 pour cent). La teigne est tres frequente et traduit des conditions socio-economiques precaires