ABSTRACT
A total of 264 children, aged less than 15 years were allocated according to their diagnostic conditions to one of seven regimens. Hundred and thirty five pulmonary and twenty five extra - pulmonary tuberculosis were allocated to five regimens, each containing the available antituberculosus drug. Bacteriological conversion, radiological changes and adverse reaction were compared. There was no relapse rates between 6 and 24 months of follow up after termination of treatment. Sixty five children were taking chemoprophylaxis of Isoniazid and thirty nine children with previous BCG vaccination were under observation. It is concluded that all the regimens are effective in treatment of tuberculosis, but, the priority to those with rifampicin because they are easy to administer and well accepted. BCG vaccination and chemoprophylaxis are protective against tuberculosis. There are a lot of reports in the world about the role of drug-therapy against tuberculosis in children. The informations about the effect of chemotherapy in Iraqi's children are still few, the purpose of this study is to evaluate the efficacy of these drugs and their acceptability by Iraqi tuberculous children