ABSTRACT
Objective: To compare the visual outcomes of phacoemulsification surgery with intraocular lens [IOL] in persons with and without diabetes at end of follow-up
Methods: This was a comparative, cross sectional, observational study with Non-probability, purposive sampling. After approval from "Research Ethical Committee of Isra Post-graduate Institute of Ophthalmology Karachi, 92 patients with cataract in one eye were selected. Patients were divided into two groups. Group A consisted of 48 diabetics and group B consisted of 44 non- diabetics with or without diabetes in the age group >/= 30 years were included. Patients with small Pupil, Pseudo exfoliation Syndrome, Diabetic Retinopathy, and positive history of Uveitis, Glaucoma, and Macular Degeneration were excluded. Data analysis was performed by SPSS Version 20.0
Results: Best Corrected Visual Acuity [BCVA] in diabetic patients improved from 0.813 +/- 0.181 Log MAR pre operatively to 0.183 +/- 0.143 after the period of six months post-operatively. Corresponding results in non-diabetics were 0.66 +/- 0.31 and 0.08 +/- 0.092 Log Mar [P value = 0.001]. If WHO criteria was considered, 87.5% diabetics and 92% non-diabetics achieved normal vision [Log Mar 0 to 0.5; >/= 6/12,] on the first postoperative day. Remaining 12.5% diabetics and 8% non-diabetics achieved moderate vision [0.6 to 1 Log MAR] on first post-operative day improving to normal vision within a week
Conclusion: Visual outcomes in diabetics after phacoemulsification with intra ocular lens implant is almost as good as that in non-diabetic patient if the diabetics have no retinopathy and have good glycemic control
ABSTRACT
Objective: To study the outcomes of intravitreal injection of Bevacizumab and laser photocoagulation in the treatment of diabetic macular edema [DME]
Methods: Seventy-two eyes of 59 patients with diabetic macular edema were divided into two groups of 41 eyes [Group-A] and 31 eyes [Group-B]. Subjects in group-A were treated with three intravitreal injections of Bevacizumab [IVB], and that of group-B with macular photocoagulation. Duration of study was 9 months. Follow up pattern for both groups was 1,2,3 and 6 months. Best Corrected Visual acuity on log AAAR [BCVA] for distance as well as near in each visitwas recorded. Retinal OCT for central macular thickness [CMT] was performed on baseline. SPSS version 20.0 was used to analyze the data
Results: Mean age of the patients was 53.76 +/- 8.82 ranging to 36-71 years. Out of 59 patients, 40 [67.8%] were male and 19 [32.2%] female. It was observed that the difference of results among both groups was not significant. Fig.2 documents visual acuity recorded as Improved; Stable and Worse. in BCVA has been almost similar between both the treatment groups although it was noted that JVB group showed early improvement in BCVA at follow-ups of 1 and 3 months. A long term follow-up is required in these cases to see the effect of both these treatment strategies