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Isra Medical Journal. 2012; 4 (1): 43-47
in English | IMEMR | ID: emr-194536

ABSTRACT

Hepatitis C is an infectious disease of viral origin primarily affecting the liver, caused by the hepatitis C virus [HCV]


The infection is usually subclinical/ asymptomatic, but chronic infection can lead to scarring of the liver and ultimately to cirrhosis leading to liver failure, hepato cellular carcinoma or life-threatening esophageal and gastric varices. The route of acquiring infection is by an exposure to blood or blood products


The virus persists in the liver in about 85% of those infected patients. Persistent infection can be treated with various anti-viral medications like peginterferon and ribavirin. Theseare amongstthe current standard therapy. Overall cure rate is between 51-80%. Those who develop cirrhosis or liver cancer may require a liver transplant, and the virus universally recurs after transplantation

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