ABSTRACT
Objective: to assess serum level of 1L -6 in RA Compared to SLE and healthy controls and to estimate serum lg Levels [IgG,IgM,IgA] in the three groups and evaluate their level in comparison to 1L6
Methods: a cross sectional study of 35 patients with RA and 25 Patients with SLE and 20 healthy [volunteers ] as control groups was conducted using immunological tests to evaluate them
Result: in this study, we found that IL-6 was detected in 19 patients [54.3%] with RA compared to patients [60%] with SLE and non of the healthy control. Serum IgG, IgA Levels were elevated in RA patients compared to the serum Level for healthy controls, although not significant statistically. There was a moderately strong linear correlation between serum IgG and IL-6 and there was a moderately strong positive linear correlation between serum IgA and IL-6
Conclusion: IL-6 was significantly higher in sera of patients with Rheumatoid arthritis, while different levels of immunoglobulin [high IgG, IgA and normal IgM] were detected