Typhoid fever with hepatic and extrahepatic manifestations

Hepatic involvement is not uncommon in typhoid fever. We report a case of typhoid fever complicated by acute hepatitis, acute choliangitis, acute acalculous cholecystitis, anaemia and severe thrombocytopenia [platelets 1x10[3]/ul]. He received antibiotics, steroids, immunoglobulin, multiple platelet and packed RBC transfusion. Fever responded and blood parameters started improving after 16th day of the treatment and patient was discharged healthy on 21st day of the admission. In conclusion, hepatic dysfunction with jaundice is a serious development in typhoid fever and patient may take longer time to respond to treatment

Cutaneous primary CD30 [Ki-1] positive large T-cell lymphoma in an HIV infected patient

A 52-year-old male with advanced human immunodeficiency virus [HIV] infection was found to have primary cutaneons and intraoral CD30 [Ki-I]-positive large T-cell lymphoma [LCL]. Primary cutaneous T-cell lymphomas have been rarely described in patients with HIV infection and should be considered in the differential diagnosis of cutaneous neoplastic and infectious diseases affecting this patient group. We report a case of primary cutaneous and intraoral presentation of large T-cell lymphoma [LCL], which was clinically believed to be bacillary angiomatosis. The diagnosis ofCD30-positive large T-cell lymphoma [LCL] was established based on histopathologic and immunohistochemical studies