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Sudan Journal of Medical Sciences. 2010; 5 (4): 247-253
in English | IMEMR | ID: emr-122321

ABSTRACT

This is a prospective comparative randomized study carried out at Kosti teaching hospital 2006- 2008. To determine the radiological findings and to evaluate the radiological progress in patient with pulmonary Tuberculosis treated with daily versus intermittent short course regimens. A total of 275 smear positive new cases of Tuberculosis were enrolled and randomized in to two groups, intermittent group [A] and daily regimen group [B] .X-Ray film was done initially and at the end of treatment for each patient. It was found that 31% of the X-Ray films were normal. Concerning the progress of minimal lesion significantly high percentage improved to normal X-Ray 58% in group A and 53% in group B, 42% in group A and 40% in group B stayed as minimal lesion. The results of far advanced lesion revealed that intermittent regimen improved 16.6% of the films to normal and minimal lesion, 8.3% to moderate lesion, 33.3% moderately advanced lesion and 25% remained unchanged, while in the daily regimen, 21% improved to normal and minimal lesion, 5.2% to moderate lesion, 27% to moderately advanced lesion and 27.6%. Statistical analysis revealed a significant difference between the two groups. Conversion of minimal lesions to normal X-Ray was significantly higher in the intermittent group and the conversion of far advanced lesions to normal was significantly higher in the daily regimen


Subject(s)
Humans , Mycobacterium tuberculosis/isolation & purification , Tomography, X-Ray Computed , Sputum/microbiology , Radiography, Thoracic , Prospective Studies
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