Peripheral sterile corneal infiltrate in two brothers after photorefractive keratectomy

This is a report of two brothers who underwent bilateral photorefractive keratectomy and developed bilateral peripheral corneal infiltrate on the third day following surgery. The patients were treated with antibiotics and low concentration steroid until negative culture was reported 48 h later, when intensive topical steroid was started. The infiltrate resolved by day 10 with residual subepithelial haze that was apparent 8 months after surgery. Sterile infiltrate has been reported as complication of photorefractive keratectomy and can be managed successfully with excellent outcome. The fact that it happened in two brothers may raise the possibility of genetic predisposition

Controlled Cyclophotocoagulation with diode laser in refractory glaucoma and long term follow up at King Abdulaziz University Hospital, Riyadh

To evaluate the clinical efficacy and safety of controlled contact transscleral diode laser Cyclophotocoagulation [COCO] procedure in reducing the Intraocular Pressure [IOP] among patients with refractory glaucoma. Thirty two patients [35 eyes] with refractory glaucoma in prospective clinical studies were treated with trans-sclera diode laser in a controlled manner. The energy power used was 5 W in adults and 3 W in children, exposure time was 0.5 s, a total of 16 shots were applied over ciliary body and four shots in each quadrant. Pre and postoperative IOP were measured at different postoperative visits. Snellen visual acuity, the number of anti-glaucoma medications and associated complications were also recorded. Student Ttest was used to compare the pre and post intervention lOPs, while Wilcoxon Signed Ranks test was used, to detect significance change in medication dependency. The mean [SD] follow up time was 80.2[ +/- 9.6] months, range [36-84] m, where the mean IOP was significantly reduced from 35.1 mm Hg [ +/- 10.7] before intervention to 18.8 mm Hg [ +/- 7.3] after intervention, in the final visit [P < 0.0001]. Complete success was achieved in seven eyes [20%], 22 eyes [62.8%] showed qualified successes and complete failure was reported in six eyes [17.1%]. The overall success rate was 82.8% [95% CI: 70.4-95.3]. Visual acuity improved