ABSTRACT
The Incidence of monoclonal proteins and their Significance among hospital patients were investigated. During eight months period out of 6060 serum protein electrophoresis performed in Medieal city Laboratory, monoclonal proteins were demonstrated in the sera of 45 patients only, corresponding to a frequancy of 0.74 per cent.Those 45 patients were studied regarding to clinical, radiological and laboratory investigatlons in an attempt to reach a final diagnosis. Of 45 patients 25 [55.5%] had plasma cell dyscrasia, 12 [26.7%] had malignant lymphoma, leukemias or carcinomas, 8 [17.8%] had inflammatory conditions and other miscellaneous associated conditions. The patients with multiple myeloma were more than half of the cases, and with immunoglobulin class of IgG and IgA only. In general, the incidence of monoclonal proteins in our patients population is lower than previously reported